Intracorneal Hemorrhage Secondary to Aphakic Contact Lens Wear

Al-Hussaini, Ashraf K.; Friedlander, Miles H.; Karcioglu, Zeynel A.

doi:10.1097/00003226-199201000-00011

Cited by 8 publications

(6 citation statements)

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“…ICH reported in dogs is limited to focal areas within 1 or 2 all corneal quadrants with no reports of ICH with an annular pattern ( 6 , 7 ). In this patient, we suspect that the main causes of ICH are, as suggested in human reports ( 4 , 5 ), the friction of the contact lens with preexisting corneal vessels and the increased fragility of newly formed vessels. Additionally, ICH would exacerbate by the high susceptibility in diabetic patients to bleeding due to upregulation of macrovascular MMP-9 activity ( 11 ).…”

Section: Discussionmentioning

confidence: 54%

“…Suggested possible factors of contact lens-induced corneal vascularization are microtrauma from the contact lens, corneal edema, extended wear, and corneal hypoxia ( 8 , 10 ). There are many reports of corneal neovascularization due to contact lens wear in humans, however, reports of ICH related to contact lenses are relatively uncommon ( 4 , 5 , 8 ).…”

Section: Discussionmentioning

confidence: 99%

“…The mainstay of ICH treatment in humans is to remove the causative contact lens ( 4 ). Although rare, there are reports of humans undergoing surgery for contact lens-related ICH such as corneal epithelial denudation, and lamellar or penetrating keratoplasty ( 4 , 5 ). In the present case, the ICH was resolved in approximately a month with the discontinuation of the contact lens and the installation of artificial tears.…”

Section: Discussionmentioning

confidence: 99%

“…While contact lens is widely used in veterinary ophthalmology, there is little available veterinary literature pertaining to the side effects of such usage. In human medicine, the literature reports many complications associated with wearing contact lenses such as mechanical trauma, corneal edema, corneal wrinkling, limbal hyperemia, reduced corneal sensitivity, corneal neovascularization, and intracorneal hemorrhage (ICH) ( 4 , 5 ).…”

Section: Introductionmentioning

confidence: 99%

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Case report: Presumed contact lens-induced intracorneal hemorrhage in a diabetic dog

Jung

Park

2022

Front. Vet. Sci.

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A 10-year-old castrated male miniature poodle dog with diabetes mellitus was presented for a week history of blepharospasm and epiphora in the right eye. The spontaneous chronic corneal epithelial defect (SCCED) was diagnosed, and a bandage contact lens was applied following corneal debridement with sterile cotton-tip applicators. In 1 week, SCCED was improving uneventfully, though an annular pattern of intracorneal hemorrhage was observed. The contact lens was removed and the intracorneal hemorrhage resorbed in 4 weeks. To the author's knowledge, this is the first report of presumed contact lens-induced intracorneal hemorrhage characterized by an annular pattern in a dog.

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Section: Discussionmentioning

confidence: 54%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Case report: Presumed contact lens-induced intracorneal hemorrhage in a diabetic dog

Jung

Park

2022

Front. Vet. Sci.

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“…There are case reports and series, albeit rare, of intracorneal hemorrhages in contact lens wearers of all modalities, including soft contact lenses, rigid gas-permeable lenses, and older-generation scleral contact lenses 8–13 . Intracorneal hemorrhages associated with contact lens use are hypothesized to be associated with hypoxia or mechanical etiologies.…”

Section: Discussionmentioning

confidence: 99%

Case Report: Intracorneal Hemorrhages Seen with Scleral Contact Lens Wear and Netarsudil Therapy

Crum¹,

Srikumaran

2022

Optom Vis Sci

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SIGNIFICANCE: Intracorneal hemorrhages are a rare finding generally associated with surgery or trauma. There is no consensus on preferred management except eliminating or addressing the causative mechanism in hopes of reducing the risk of corneal haze or scarring. PURPOSE: This case highlights a rare adverse outcome of intracorneal hemorrhages occurring after recent initiation of netarsudil, possibly exacerbated by scleral contact lens wear in a patient with open-angle glaucoma and limbal stem cell deficiency. CASE REPORT: A 77-year-old man using scleral contact lenses for therapeutic management of limbal stem cell deficiency started netarsudil for open-angle glaucoma. During an annual follow-up to adjust his scleral contact lenses, the patient developed peripheral intracorneal hemorrhages bilaterally. The intracorneal hemorrhages resolved over the course of 10 weeks after minor adjustments were made to the scleral contact lens fit and netasurdil was discontinued. Visual acuity and intraocular pressure remained stable throughout.CONCLUSIONS: There are few reports of intracorneal hemorrhages associated with scleral contact lens use and even fewer associated with the use of netarsudil. This case proposes several possible causes of the intracorneal hemorrhages, including topical rho-associated kinase inhibitors, contact lens wear, and trauma. Further studies are needed to determine if netarsudil is associated with intracorneal hemorrhages, to understand the sequelae of intracorneal hemorrhages in netarsudil therapy, and to recommend management when intracorneal hemorrhages manifest with netarsudil use.

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Layered pre-descement intracorneal hemorrhage in a patient with end-stage glaucoma

et al. 2002

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Intracorneal Hemorrhage Secondary to Aphakic Contact Lens Wear

Cited by 8 publications

References 0 publications

Case report: Presumed contact lens-induced intracorneal hemorrhage in a diabetic dog

Case report: Presumed contact lens-induced intracorneal hemorrhage in a diabetic dog

Case Report: Intracorneal Hemorrhages Seen with Scleral Contact Lens Wear and Netarsudil Therapy

Layered pre-descement intracorneal hemorrhage in a patient with end-stage glaucoma

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