Intraclass correlations: Uses in assessing rater reliability.

Shrout, Patrick E.; Fleiss, Joseph L.

doi:10.1037/0033-2909.86.2.420

Cited by 19,826 publications

(14,032 citation statements)

References 21 publications

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“…A p value of less than .05 was statistically significant. The intraclass correlation coefficient (ICC) of the two reader's measurements was determined by using the Shrout-Fliess Random test [11] …”

Section: Resultsmentioning

confidence: 99%

Simple linear measurements of the normal liver: interobserver agreement and correlation with hepatic volume on MRI

et al. 2010

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Section: Resultsmentioning

confidence: 99%

Simple linear measurements of the normal liver: interobserver agreement and correlation with hepatic volume on MRI

et al. 2010

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“…An intraclass correlation (ICC) analysis [29] was performed to test the interobserver and intraobserver concordance of the bone marrow plasma cell percentages, for all the 79 cases, obtained with the various methods of evaluation (Wright-Giemsa-stained aspirate smears, HE sections, and CD138 sections). Using this method, an ICC value of 1 denotes a perfect interobserver concordance.…”

Section: Resultsmentioning

confidence: 99%

Assessment of bone marrow plasma cell infiltrates in multiple myeloma: the added value of CD138 immunohistochemistry

et al. 2007

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SummaryAssessment of bone marrow involvement by malignant plasma cells is an important element in the diagnosis and follow-up of patients with multiple myeloma and other plasma cell dyscrasias. Microscope-based differential counts of bone marrow aspirates are used as the primary method to evaluate bone marrow plasma cell percentages. However, multiple myeloma is often a focal process, a fact that impacts the accuracy and reliability of the results of bone marrow plasma cell percentages obtained by differential counts of bone marrow aspirate smears. Moreover, the interobserver and intraobserver reproducibility of counting bone marrow plasma cells microscopically has not been adequately tested. CD138 allows excellent assessment of plasma cell numbers and distribution in bone marrow biopsies. We compared estimates of plasma cell percentages in bone marrow aspirates and in hematoxylin-eosin-and CD138-stained bone marrow biopsy sections (CD138 sections) in 79 bone marrows from patients with multiple myeloma. There was a notable discrepancy in bone marrow plasma cell percentages using the different methods of observation. In particular, there was a relatively poor concordance of plasma cell percentage estimation between aspirate smears and CD138 sections. Estimates of plasma cell percentage using CD138 sections demonstrated the highest interobserver concordance. This observation was supported by computer-assisted image analysis. In addition, CD138 expression highlighted patterns of plasma cell infiltration indicative of neoplasia even in the absence of plasmacytosis. We conclude that examination of CD138 sections should be considered for routine use in the estimation of plasma cell load in the bone marrow.

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“…75 The inter-rater or intrarater reliability that researchers achieve varies greatly across studies and ranges from 0.64 to 0.99. Of the 115 'original' protocols, 60 (52%) report ICCs, 76 inter-rater or intrarater reliability values greater than 0.90. In all, 25 protocols (21%) report values of 0.80-0.89 and 6% of the protocols report values lower than 0.80.…”

Section: Image Processingmentioning

confidence: 99%

MR-based in vivo hippocampal volumetrics: 1. Review of methodologies currently employed

2004

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The advance of neuroimaging techniques has resulted in a burgeoning of studies reporting abnormalities in brain structure and function in a number of neuropsychiatric disorders. Measurement of hippocampal volume has developed as a useful tool in the study of neuropsychiatric disorders. We reviewed the literature and selected all English-language, human subject, data-driven papers on hippocampal volumetry, yielding a database of 423 records. From this database, the methodology of all original manual tracing protocols were studied. These protocols differed in a number of important factors for accurate hippocampal volume determination including magnetic field strength, the number of slices assessed and the thickness of slices, hippocampal orientation correction, volumetric correction, software used, inter-rater reliability, and anatomical boundaries of the hippocampus. The findings are discussed in relation to optimizing determination of hippocampal volume.

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Intraclass correlations: Uses in assessing rater reliability.

Abstract: Models for Reliability Studies In a typical interrater reliability study, each of a random sample of n targets is rated independently by k judges. Three different

Cited by 19,826 publications

References 21 publications

Simple linear measurements of the normal liver: interobserver agreement and correlation with hepatic volume on MRI

Simple linear measurements of the normal liver: interobserver agreement and correlation with hepatic volume on MRI

Assessment of bone marrow plasma cell infiltrates in multiple myeloma: the added value of CD138 immunohistochemistry

MR-based in vivo hippocampal volumetrics: 1. Review of methodologies currently employed

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