Intracerebral Astrocytoma in a Horse

Cavasin, João Pedro; Miller, Andrew D.; Duhamel, G

doi:10.1016/j.jcpa.2020.03.009

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Tumours and Other Endogenous Antigens1

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2022

2023

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Cited by 2 publications

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“…This antibody is usually employed when dealing with CNS tumours, especially to confirm astrocytomas. Olig‐2 is an antibody used to label oligodendrocytes (and oligodendrogliomas) in multiple animal species; in the horse, Olig‐2 IHC is seldom reported, suggesting it is a valid antibody also in the equine species (Cavasin et al, 2020). Neuronal markers valid in equine pathology include S‐100 (which is also considered a melanocytic one), PGP 9.5, synaptophysin and neuronal‐specific enolase (NSE).…”

Section: Tumours and Other Endogenous Antigensmentioning

confidence: 99%

Immunohistochemistry in equine pathology: A brief overview

Rocchigiani

Ressel

2023

Equine Veterinary Education

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IHC uses primary antibodies to highlight any type of antigen expressed by normal host cells, viruses, bacteria and tumoural cells, and such versatility made IHC an invaluable tool for research focussing at the same time on protein expression and morphology. While IHC more deep technical aspects are beyond the scope of this manuscript and will therefore not be discussed (for additional data, see Ramos-Vara & Miller, 2014), we will briefly discuss the importance of IHC in equine diagnostic pathology, condensed in a few paragraphs.All the IHC markers mentioned in the present study refer to IHC performed on formalin-fixed paraffin-embedded (FFPE) tissue, as this represents the most diffuse IHC used in veterinary pathology.

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Section: Tumours and Other Endogenous Antigensmentioning

confidence: 99%