“…This can involve both the targets within the microbe and the host’s transporters when (as is common, e.g., [ 468 , 469 , 470 , 471 , 472 , 473 , 474 , 475 , 476 , 477 , 478 , 479 , 480 , 481 , 482 , 483 , 484 , 485 ]) the infective agents reside intracellularly. A particularly clear example is given by Mycobacterium tuberculosis , the causative agent of TB, where the very striking lack of correlation between in vivo and in vitro drug potencies is easily and necessarily explained via transporter activities [ 139 , 151 , 486 , 487 , 488 ]. Many orally prescribed antibiotics enter the host via SLC15 family members [ 489 , 490 ], while some of the relatively few known microbial uptake transporters for anti-infectives are listed in Table 1 .…”