Intracellular Fluorometric Recognition of Explosive and Mutagenic Nitroaromatics by a Luminescent Phenanthrene‐Naphthalene Sulfone

Abstract

Luminescent phenanthrene‐naphthalene sulfone has been synthesized having phenanthrene and naphthalene as antenna center with an aim of fluorogenic in vitro detection of highly mutagenic NACs, which are hitherto less explored. The chemosensor could detect NACs selectively over NALs of which TNP detection is highly selective by a swing in fluorescence spectrum from 405 to ∼475 nm with extremely high quenching constant 1.93×105 M−1 and LOD 100 nM. Fluorometric recognition of TNP was explained through a combined complex PET‐RET‐ACQ‐CT pathway. DFT calculation has been performed to obtain the low energy configuration of the host⋅⋅⋅guest adduct. NMR titration reveals the chemical stability of the host in presence of TNP, suggests that the interaction belongs to supramolecular realm that supports the utilization of the chemosensor forin vitro detection of TNP within pollens of Tecoma Stans, Peperomia roots and Candida Albicans, indeed establishes the scaffold as a biocompatible chemosensor.

One-pot synthesis of poly(vinylpyrrolidone)-encapsulated color-emitting silicon quantum dots for sensitive and selective detection of 2,4,6-trinitrophenol

“…Compared with some previous TNP probes (Table S1, ESI†), the PVP-Si QDs showed moderate linear range and sensitivity for TNP detection; it is easy to prepare and advantageous in its comprehensive ability. 25–28,33,51–53…”

“…Compared with some previous TNP probes (Table S1, ESI †), the PVP-Si QDs showed moderate linear range and sensitivity for TNP detection; it is easy to prepare and advantageous in its comprehensive ability. [25][26][27][28]33,[51][52][53] Selectivity of the PVP-Si QDs for TNP sensing Zn 2+ , Hg 2+ , Cu 2+ , Cr 3+ , Fe 2+ and Al 3+ ) and anions (F À , Cl À , Br À , I À , CN À , SCN À , ClO ) were studied under the same test conditions. As shown in Fig.…”