Intracardiac shear wave velocimetry using Acoustic Radiation Force (ARF) excitations: In vivo results

Hollender, Peter; Wolf, Patrick D.; Trahey, Gregg E.

doi:10.1109/ultsym.2011.0006

Cited by 2 publications

(1 citation statement)

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“…ICE is commonly used for function assessment and therapy guidance [25]–[29], and has already been shown to be feasible for cardiac ARFI imaging [30], [31]. Because the imaging transducer is located so close to the myocardium, less ultrasonic energy is needed to excite the tissue, and the response can be imaged without the clutter associated with imaging across the chest wall.…”

Section: Introductionmentioning

confidence: 99%

Intracardiac acoustic radiation force impulse (ARFI) and shear wave imaging in pigs with focal infarctions

Hollender

Bradway

Wolf

et al. 2013

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

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Four pigs, three with focal infarctions in the apical intraventricular septum (IVS) and/or left ventricular free wall (LVFW), were imaged with an intracardiac echocardiography (ICE) transducer. Custom beam sequences were used to excite the myocardium with focused acoustic radiation force (ARF) impulses and image the subsequent tissue response. Tissue displacement in response to the ARF excitation was calculated with a phase-based estimator, and transverse wave magnitude and velocity were each estimated at every depth. The excitation sequence was repeated rapidly, either in the same location to generate 40 Hz M-Modes at a single steering angle, or with a modulated steering angle to synthesize 2-D displacement magnitude and shear wave velocity images at 17 points in the cardiac cycle. Both types of images were acquired from various views in the right and left ventricles, in and out of infarcted regions. In all animals, ARFI and SWEI estimates indicated diastolic relaxation and systolic contraction in non-infarcted tissues. The M-Mode sequences showed high beat-to-beat spatio-temporal repeatability of the measurements for each imaging plane. In views of noninfarcted tissue in the diseased animals, no significant elastic remodeling was indicated when compared to the control. Where available, views of infarcted tissue were compared to similar views from the control animal. In views of the LVFW, the infarcted tissue presented as stiff and non-contractile compared to the control. In a view of the IVS, no significant difference was seen between infarcted and healthy tissue, while in another view, a heterogeneous infarction was seen presenting itself as non-contractile in systole.

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Section: Introductionmentioning

confidence: 99%