Intracanalicular meningioma: diagnostic by immunohistochemistry

Borin, Andrei; Okada, Daniel Mochida; Cruz, Oswaldo Laércio Mendonça

doi:10.1016/s1808-8694(15)30769-2

Cited by 1 publication

(2 citation statements)

References 5 publications

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“…It has been noted that immunoreactivity for epithelial membrane antigen and keratin will be strongly positive in meningiomas, but negative or only weakly positive in schwannomas. 10 . Meningiomas make up 18 per cent of primary intracranial tumours, whereas the estimated incidence of extracranial meningiomas is only 2 per cent.…”

Section: Discussionmentioning

confidence: 99%

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Primary meningioma of the middle ear: case report

et al. 2009

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Objective: To report a rare case of primary meningioma of the middle ear.Method: We describe the case of a 55-year-old woman who presented with decreased hearing and fullness in the left ear, with a middle-ear mass. We also review the world literature regarding primary extracranial meningioma of the middle ear and its management.Results: Primary middle-ear meningioma, a rare clinical entity, was diagnosed in this patient based on an initial transmastoid biopsy. Magnetic resonance imaging with gadolinium enhancement excluded the presence of an intracranial component. Complete excision of the tumour was achieved using a combined approach tympanoplasty. The patient had an uneventful post-operative course.Conclusion: Meningiomas, although rare in the middle ear, need to be included in the differential diagnosis of middle-ear lesions presenting to the otolaryngologist. This case emphasises the management strategy required when dealing with a middle-ear mass.

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Section: Discussionmentioning

confidence: 99%

“…The immunohistochemical profile of meningioma is quite characteristic, and is useful in differentiating these tumours from schwannoma. It has been noted that immunoreactivity for epithelial membrane antigen and keratin will be strongly positive in meningiomas, but negative or only weakly positive in schwannomas 10 …”

Section: Discussionmentioning

confidence: 99%