Intraabdominal Infections in the Intensive Care Unit

Abstract

Intraabdominal infections are frequent and dangerous entity in intensive care units. Mortality and morbidity are high, causes are numerous, and treatment options are variable. The intensivist is challenged to recognize and treat intraabdominal infections in a timely fashion to prevent complications and death. Diagnosis of intraabdominal infection is often complicated by confounding underlying disease or masked by overall comorbidity. Current research describes a wide heterogeneity of patient populations, making it difficult to suggest a general treatment regimen and stressing the need of an individualized approach to decision making. Early focus-oriented intervention and antibiotic coverage tailored to the individual patient and hospital is warranted.

Anaerobic Infections

“…Causes of intra-abdominal infections in the intensive care unit were recently reviewed [73]. Secondary peritonitis after disruption of the intact intra-abdominal barrier can occur due to inflammation, cancer, injury, or leakage from anastomic sites or other sites of superinfection.…”

Novel multiparametric nomogram for overall survival prediction in complicated intra-abdominal infection: A multicenter study in China

“…Achieving prompt control over infection of an anatomic source is the cornerstone of cIAI management but is not always successful [4]. Several risk factors including delayed interventions, antibiotic-resistant pathogens, high severity of illness, advanced age, poor nutritional status, and pre-existing chronic medical conditions have been reported to cause treatment failure [6][7][8][9]. Early clinical evaluation is essential for the illness strati cation and the subsequent decision-making process, and even for auditing and research.…”

Komplike İntraabdominal Enfeksiyonların Cerrahi Tedavi ve Sonuçlarının Analizi

“…The complicated intra-abdominal infection (cIAI) is defined as the bacterial invasion of otherwise sterile peritoneal environment through perforation of hollow viscus, such a appendicitis or colonic diverticulitis, or by other irritants, such as bile from a perforated gall bladder or lacerated liver, gastric acid from a perforated ulcer, or an infected fallopian tube or ruptured ovarian cyst in women (1,2). The cIAI can be localized or extend to other organs causing diffuse peritonitis.…”

“…The common clinical symptoms of cIAI are abdominal pain and tenderness, nausea, diminished intestine sounds, high fever, hypotension and tachycardia. However, diagnosis is based on the radiological imaging studies including abdominal and chest radiography, ultrasonography, and computed tomography (1,2,5,7,9).…”