Intra-Vesical Colistin for Pseudomonas aeruginosa Urinary Tract Infections

Assis, Rui; Coelho, Inês; Real, A. P.; França, Luís; Araújo, A. M.; Pereira, T.; Catorze, Nuno

doi:10.12890/2019_000996

Cited by 3 publications

(3 citation statements)

References 6 publications

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“…Although the type of publications about intravesical instillation are either case reports or case series, intravesical instillation has shown to be effective in decreasing the rate of recurrent infections. [4142]…”

Section: Intravesical Antibioticsmentioning

confidence: 99%

Management of urinary tract infection in women: A practical approach for everyday practice

et al. 2019

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A common health-care problem worldwide, urinary tract infection (UTI), represents a disease of significant impact on every country's economy, being the most common cause of hospitalization among elderly people and the most common cause of antibiotic prescription in primary care. Diagnosing and managing upper and lower UTI have always been a challenge to physicians, given its high prevalence, risk of recurrence and improper treatment, and the fact of worldwide increase in antibiotic resistance, necessitating implementation of a proper antibiotic stewardship. Urinary infections are twice more likely to occur in females compared to males and its prevalence increases with increasing age. The following is a comprehensive review paper about UTI in females, discussing the various factors leading to a complicated infection. The various etiologies and microbiologies of UTI are also highlighted. In addition to various usual antibiotic regimens for treating UTI, a significant number of nonantimicrobial treatment modalities are highlighted and described in this manuscript, including the novel use of intravesical antibiotics and vaccines for suppression treatment. Finally, a pathway is suggested for the proper diagnosis and treatment that ensures antibiotic stewardship in order to decrease long-term complications.

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Section: Intravesical Antibioticsmentioning

confidence: 99%

Management of urinary tract infection in women: A practical approach for everyday practice

et al. 2019

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“…We found neither Multidrug-Resistant (MDR) organisms such as Klebsiella pneumoniae Carbapenamase-resistant ( KPC ) bacteria among the bacterial isolates nor Acinetobacter or Pseudomonas aeruginosa MDR ; thus, there was no need to consider Colistin intravesical instillation, as reported by some authors [ 11 , 12 ].…”

Section: Discussionmentioning

confidence: 60%

Intravesical Gentamicin: An Option for Therapy and Prophylaxis against Recurrent UTIs and Resistant Bacteria in Neurogenic Bladder Patients on Intermittent Catheterization

Andretta¹,

Longo²,

Balladelli³

et al. 2022

Antibiotics

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“…In this investigation, the aftereffects of TUNEL staining were correlated with those of tryptase staining, demonstrating that constant irritation of the suburothelium was essentially connected with more significant levels of urothelial apoptosis in the bladders of patients with ESRD/CKD. These associations show that aggravation caused expanded apoptosis and influenced urothelial tangible capacity in ESRD/CKD patients [11].…”

Section: Discussionmentioning

confidence: 87%

Clinicopathological Analysis of Chronic Urothelial Inflammation Associated with UTI in Women

Aalam¹,

Ashraf²,

Muhammad³

2022

PJMHS

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Introduction: Urinary tract infection (UTI) is a typical grumbling experienced in outpatient setting, regardless of whether essential care or expert facility. Objectives of the study: The basic aim of the study is to analyses the clinicopathological analysis of chronic urothelial inflammation associated with UTI in women. Material and methods: This cross sectional study was conducted in Foundation University Medical College Islamabad During March 2021 till November 2021. The data was collected through non-probability consecutive sampling technique. Results: The data was gathered from 100 patients. The examination of data shows the distinctions in urodynamic factors between the control subjects and the ESRD/CKD patients. In general, the ESRD/CKD patients had fundamentally lower FS, US, and CBC than did the controls. Patients with ESRD/CKD with DU had altogether lower FS, CBC in ESRD/DU patients with BO (table 01). Conclusion: It is concluded from our study that chronic inflammation, urothelial cell apoptosis and impairment of barrier function of urothelial cells could be the underlying pathophysiology of recurrent UTI in women. Keywords: UTI, Women, Pathology, Urothelial

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Intra-Vesical Colistin for Pseudomonas aeruginosa Urinary Tract Infections

Cited by 3 publications

References 6 publications

Management of urinary tract infection in women: A practical approach for everyday practice

Management of urinary tract infection in women: A practical approach for everyday practice

Intravesical Gentamicin: An Option for Therapy and Prophylaxis against Recurrent UTIs and Resistant Bacteria in Neurogenic Bladder Patients on Intermittent Catheterization

Clinicopathological Analysis of Chronic Urothelial Inflammation Associated with UTI in Women

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