Perinatal testicular torsion (PTT) is almost exclusively extravaginal and often presents nontender unilateral scrotal enlargement. 1 The torsion occurs outside the tunica vaginalis when the testes and gubernacula are not fixed and are free to rotate. Bilateral spermatic cord torsion in the newborn is an extremely rare event, and emergency exploration is indicated because of the risk of anorchia. 2,3 We present here a case with bilateral testicular torsion.
Case reportA 32-year-old woman, gravida 1 para 0, was referred to our institution because of a fetal tachyarrhythmia at 33 weeks of gestation. Fetal echocardiography showed an atrial flutter with regular atrial wall motion of 410 b.p.m. at a rate of 2 : 1 to ventricular wall motion. The fetus was not hydropic and no structural cardiac abnormality was detected. Transplacental digoxin therapy successfully converted the atrial flutter in two days to a normal sinus rhythm without evidence of maternal or fetal side-effects. Routine prenatal ultrasonography showed no pathology.At 39 weeks of gestation, a 4020-g, large-for-gestational-age male infant was born by cesarean section. The physical examination revealed a bilateral swelling of the scrotum, which was negative to transillumination, and mobile, firm and tender testes. No discoloration of the scrotum was noted. Color Doppler ultrasound examination of the testicles showed a homogeneous structure without intratesticular Doppler signal. The laboratory evaluation disclosed normal white blood cell count and acute phase reactants, including C-reactive protein and interleukin-6.Within 3 h, the infant underwent emergency exploration by bilateral inguinal incision. At operation, both testes were black, hemorrhagic and necrotic with extratunical twists in the cords bilaterally, confirming the clinical suspicion of advanced infarction. The left testicle was atrophic (Fig. 1). Although a capsular bleed test was negative after detorsion, the testes were returned into the scrotum for any possible return of viability. The postoperative course of the patient was uneventful.At 12-month follow up, ultrasound examination showed bilateral atrophic testes and clear calcification with no intratesticular color Doppler signal. Hormone assay revealed a high level of basal follicle-stimulating hormone and low testosterone level. A human chorionic gonadotropin (hCG) stimulation test (5000 IE/m 2 ) demonstrated no response of serum testosterone. Inhibin B, an established marker of Sertoli cell function, was 7 pg/mL (reference range: 68-630 pg/mL). A bilateral orchiectomy with placement of testicular prostheses and supportive hormonal therapy at puberty was planned.
DiscussionThe management of unilateral PTT is somewhat controversial due to the poor salvage rate and the low risk of contralateral torsion. 4,5 Controversy exists with regard to timing of the operation and the necessity of contralateral exploration and orchiopexy, and treatment of necrotic testes.Experimental studies of testicular ischemia in dogs have shown a loss of spermatog...