Intra-stent tissue evaluation within bare metal and drug-eluting stents &gt;3years since implantation in patients with mild to moderate neointimal proliferation using optical coherence tomography and virtual histology intravascular ultrasound

Kitabata, Hironori; Loh, Joshua P.; Pendyala, Lakshmana; Omar, Alfazir; Ota, Hiroyoshi; Minha, Sa’ar; Magalhães, Marco A.; Torguson, Rebecca; Chen, Fang; Satler, Lowell F.; Pichard, Augusto D.; Waksman, Ron

doi:10.1016/j.carrev.2014.01.009

Cited by 6 publications

(3 citation statements)

References 28 publications

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“…Smaller stent is prone to suffer from neoatherosclerosis than larger stent should be addressed in another study. 23) To avoid stent-in-stent that may lead to lumen narrowing, we selected the treatment with DCB. There has not been established treatment for the neoatherosclerosis, so further study is needed to treat the neoatherosclerosis.…”

Section: A Case Reportmentioning

confidence: 99%

Very Late In-stent Restenosis due to Neoatherosclerosis in the Second-generation Everolimus-eluting Stent

et al. 2016

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Section: A Case Reportmentioning

confidence: 99%

Very Late In-stent Restenosis due to Neoatherosclerosis in the Second-generation Everolimus-eluting Stent

et al. 2016

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“…Subsequent studies have shown lower prevalence ranging between 30 and 50 % in long-term follow-up of asymptomatic patients with BMS [ 26 – 28 ]; however, this incidence could be as high as 100 % in BMS restenosis more than 10 years since implantation [ 29 ]. With regard to neoatherosclerosis within DES, a prevalence of more than 50 % has been reported in a very late follow-up [ 27 , 28 ], which can be even higher in stents with failure [ 14 ]. These rates tend to generally be in accordance with rates reported by pathological studies, which show a prevalence of 13–65 % depending on stent type and stent age [ 25 ].…”

Section: In Vivo Prevalence Of Neoatherosclerosis In Bms and Des Withmentioning

confidence: 99%

OCT-Nachweis einer Neoatherosklerose als Teil des fortlaufenden Prozesses der koronaren Herzkrankheit

Zhang

Καρανάσος

Regar

2015

Herz

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Although the advent of drug-eluting stents has reduced the rates of target vessel revascularization, there are observations of ongoing stent failure occurring very late after stent implantation and presenting as very late restenosis or as very late stent thrombosis. The de novo development of atherosclerosis within the neointimal region, called neoatherosclerosis, has been identified as one of the pathomechanisms of these observed late stent failures. The mechanisms of neoatherosclerosis development and its association with stent failure are currently the subject of intensive research. Optical coherence tomography (OCT) is an invasive imaging modality that allows us to visualize the micromorphology of coronary arteries with near-histological resolution, thus providing detailed assessment of the morphological characteristics of the neointima after stent implantation, including neoatherosclerosis. Several OCT studies have tried to provide in vivo insights in the mechanisms of neoatherosclerosis development and its association with late stent failure. This review summarizes the current insights into neoatherosclerosis obtained with OCT and discusses the association of neoatherosclerosis with late stent failure.

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“…There was no statistically significant difference with regard to the in-stent tissue composition, including necrotic core and dense calcium. 21…”

Section: From the Backscatter Radiofrequency Data Different Types mentioning

confidence: 99%

Intravascular Ultrasound-based Imaging Modalities for Tissue Characterisation

Ērglis

Jēgere

Narbute

2014

Interventional Cardiology Review

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Atherosclerosis is the leading cause of cardiovascular mortality and morbidity in the developed world. Intravascular ultrasound (IVUS) is a widely used imaging modality providing complementary diagnostic information to angiography regarding the vessel wall of the coronary arteries. IVUS has been used for assessment of ambiguous angiographic lesions, evaluation of new interventional devices and in atherosclerosis progression-regression trials. However, the standard gray-scale IVUS has limited value for the accurate identification of specific plaque components. This limitation has been partially over- come by introduction of new IVUS-based imaging methods such as: virtual histology IVUS, iMAP-IVUS and Integrated Backscatter IVUS. These methods utilise the ultrasound backscatter signal to enable a more detailed characterization of plaque morphology or tissue characterization and to provide insight on the features of vulnerable plaque.

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Intra-stent tissue evaluation within bare metal and drug-eluting stents >3years since implantation in patients with mild to moderate neointimal proliferation using optical coherence tomography and virtual histology intravascular ultrasound

Cited by 6 publications

References 28 publications

Very Late In-stent Restenosis due to Neoatherosclerosis in the Second-generation Everolimus-eluting Stent

Very Late In-stent Restenosis due to Neoatherosclerosis in the Second-generation Everolimus-eluting Stent

OCT-Nachweis einer Neoatherosklerose als Teil des fortlaufenden Prozesses der koronaren Herzkrankheit

Intravascular Ultrasound-based Imaging Modalities for Tissue Characterisation

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