Intra-osseous sphenoorbital schwannoma

Abstract

A 40-year-old man without stigmata of neurofibromatosis presented with proptosis and impairment of lateral gaze of the left eye. Neuro-imaging studies revealed an extra-axial lytic spheno-orbital mass. The mass was completely removed. Classic schwannoma was documented histopathologically. Schwannosis or hyperplasia of Schwann cells of perivascular nerve plexus may be attributed in the histogenesis of this unusually located schwannoma.

Intraosseous schwannoma in the clivus mimicking chordoma treated with endoscopic endonasal surgery: A case report

“…the petrous bone in eight cases, [8,11,20,23,25,29,30] frontal bone in three, [1,4,9] occipital bone in two, [4,17] parietal bone in one, [7] frontoparietal bone in one, [14] fronto-orbital bone in one, [26] and spheno-orbital bone in one. [6] To the best of our knowledge, schwannomas involving the clivus have not yet been reported. e origin of the tumor is presumed on the basis of the tumor location on imaging and neurological and intraoperative findings.…”

Solitary intraosseous schwannoma of the base and vault of the skull: a summary review of such unusual location

“…Data are available from published isolated case reports and small case series. The first documented case in the literature was published by Solodnik and al in 1986 [ 5 , 14 ].…”

“…In fact, hyperplastic schwann cells of the perivascular nerve plexus, especially of autonomic nerves could explain the development of meningeal schwannoma [ 17 ], and even intraosseous schwannoma [ 18 ]. Also, schwannosis which is an hamartomatous lesion consisting of Schwann cells and related reticulin fibers could not be excluded in histogenesis of such lesion [ 5 , 19 ].…”

“… ? Celli et al (1998) [ 24 ] 14-year Male Frontal bone Hard non tender mass Complete excision 2 year Good 3-year Male Occipital bone Hard non tender mass Complete excision 14 year Good Ersahin et al (2000) [ 13 ] 4-year Male Parietal bone A non tender solid mass Totalexcision 2 year Good El bahy and al (2004) [ 5 ] 40-year Male Spheno-orbital bone Proptosis, swelling of the frontozygomatic junction Complete excision ? Good Goyal R et al (2008) [ 2 ] 11-year Male Frontal bone Forehead swelling Complete excision 6 month Good Amita et al (2014) [ 25 ] 41-year Female Frontal bone Paresthesia of limbs, hemicranial headache, generalized tonic-clonic seizures Complete excision 3 months Good …”

“…Sphenoidal schwannoma resembles other primary tumors of the sphenoid in symptomatology and physical signs [ 5 , 6 ]. In fact, El bahy and al reported a case of spheno-orbital bone of a 40-year-old man with proptosis and impairment of lateral gaze movement of his left eye and a palpable soft non tender swelling at the left frontozygomatic junction [ 5 ].…”