Intra-Osseous Anchorage of Dental Prostheses

Adell, R; Hansson, Bengt‐Göran; Brånemark, Per‐Ingvar; Breine, U

doi:10.3109/02844317009038440

Cited by 169 publications

(38 citation statements)

References 28 publications

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“…The polyurethane foam is reticulated and subsequently pyrolysed, resulting in a low-density reticulated vitreous carbon (RVC) skeleton that can be machined or crushed into a variety of shapes or pre-forms. The vitreous carbon pre-forms are in turn transformed into Trabecular Metal s by means of a proprietary chemical vapour deposition (CVD), during which commercially pure tantalum is deposited throughout the RVC pre-forms [90].…”

Section: Vapour Depositionmentioning

confidence: 99%

Fabrication methods of porous metals for use in orthopaedic applications

2006

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Section: Vapour Depositionmentioning

confidence: 99%

Fabrication methods of porous metals for use in orthopaedic applications

2006

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“…Dental implants, pioneered by Brånemark, have been used successfully to treat edentulous patients since the 1960s (Adell et al, 1970;Marks et al, 2001;Odman et al, 1988). They have been shown to be safe and reliable, with survival rates of over 90 % at 15 years (Adell et al, 1986;Brånemark et al, 1982;Tillander et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Intraosseous transcutaneous amputation prostheses versus dental implants: A comparison between keratinocyte and gingival epithelial cell adhesion in vitro

Pendegrass

Lancashire²,

Fontaine³

et al. 2015

eCM

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Infection is the primary failure modality for transcutaneous implants because the skin breach provides a route for pathogens to enter the body. Intraosseous transcutaneous amputation prostheses (ITAP) are being developed to overcome this problem by creating a seal at the skinimplant interface. Oral gingival epithelial cell attachment creates an infection-free seal around dental implants. However, this has yet to be achieved consistently outside of the oral environment. Epithelial cells attach to metal substrates by means of hemidesmosomes and focal adhesions. Their density per unit cell is an indicator of attachment strength. We postulate that gingival epithelial cells express more hemidesmosomes and focal adhesions at earlier time points, compared with epidermal keratinocytes, and this increased speed and strength of attachment may be the reason why an infection-free seal is often achieved around dental implants but less frequently around ITAP. The aim of this study was to compare epidermal keratinocyte with oral gingival cell attachment on titanium alloy in vitro, to determine whether these two cell types differ in their speed and strength of attachment. We aimed to test the hypothesis that gingival cells up-regulate focal adhesion and hemidesmosome formation at earlier time points compared with extra-oral keratinocytes. To test this hypothesis we cultured epidermal keratinocytes and oral gingival cells on titanium alloy substrates and assessed cell attachment by focal adhesions and hemidesmosome expression at 4, 24, 48 and 72 hours. Formation and expression of hemidesmosomes temporally lagged behind that of focal adhesions in both cell types. Gingival derived cells up-regulated focal adhesion and hemidesmosome expression at earlier time points compared with epidermal keratinocytes. Hemidesmosome expression in oral gingival cells was 3 times greater compared with epidermal keratinocytes at 4 hours. Our findings indicate that earlier attachment may be key to the success of the dental implant transcutaneous interface.

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“…After this was initially demonstrated and established histologically in animal experiments [1,5], it was confirmed in human applications for dental implants first by mobility tests [6,7], measurements of the damping and recoil behavior after controlled impacts on teeth and implant supported crowns [ 8 ], and later also confirmed histologically [9]. The observation that the percussion sound is a relatively good indication of degree of osseointegration facilitated the testing of the kind of implant fixation considerably [10].…”

Section: Performance Criteria For Different Parts Of Dental Implantsmentioning

confidence: 96%

Follow‐Up Studies Based Material Selection for Dental Implants

Heimke

Hund²

2000

Materials for Medical Engineering

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Osseointegrated dental implants have reached the same high levels of success rates as most other well established dental procedures since the nineteen seventies. Different portions of dental implants must serve rather different purposes. The intraosseous part has to provide for a stable, load transmitting osseointegration, the pergingival portion must allow for a safe and reliable attachment of the gingiva to the surface of the implant and should be as plaque resistant as possible. The results of follow-up evaluations of osseointegrated dental implants published during the last about thirty years allow conclusions about the performances of different materials at the different portions of the implants. Whilst titanium, some of its alloys and eventually together with coatings of hydroxyl-apatite ceramics have been shown to perform well at the intraosseous part, alumina ceramics were found to provide for the most reliable closure of the gingiva and, surprisingly, nearly no plaque could be detected on their surfaces. Thus, a still further increase of the survival rates of dental implants can be expected from composite implants with alumina ceramic surfaces along the per-gingival part if the creation of new problems like the use of less compatible materials for joining the different parts or the occurrence of crevices in this highly sensitive area can be avoided.

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Intra-Osseous Anchorage of Dental Prostheses

Cited by 169 publications

References 28 publications

Fabrication methods of porous metals for use in orthopaedic applications

Fabrication methods of porous metals for use in orthopaedic applications

Intraosseous transcutaneous amputation prostheses versus dental implants: A comparison between keratinocyte and gingival epithelial cell adhesion in vitro

Follow‐Up Studies Based Material Selection for Dental Implants

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