Intra-operative fractures in primary total knee arthroplasty - a systematic review

Abstract

Background One of the rare complications of primary total knee arthroplasty is intra-operative fracture. Intra-operative fracture during revision knee arthroplasty has been well-documented but there is limited literature on fractures occurring during primary knee arthroplasty. We conducted a systematic review of the literature to compare and contrast the various studies to clearly define the predisposing factors, incidence, and characteristics of the fracture itself and to arrive at a consensus on the management and prevention of intra-operative fractures during primary knee arthroplasty. Methods The PubMed/Medline, Cochrane, Scopus and Embase databases were searched using keywords “intra-operative fracture”, “distal femoral fracture”, “tibial fracture”, “patella fracture” and “primary total knee arthroplasty”. A total of 158 articles were retrieved and after further filtration and exclusion processing, 10 articles that evaluated intra-operative fractures in primary total knee arthroplasty were included for the review. Results The reported incidence of intra-operative fractures varied from 0.2% to 4.4%. A higher incidence in female patients with a male to female ratio of 0.4 was reported. Posterior stabilized (PS) total knee arthroplasty was associated with higher risk of intra-operative femoral fractures by many authors in this review. Timing of occurrence and location of the intra-operative fractures can vary widely, with femoral fractures occurring more commonly during bone preparation, trialing and impaction of the final implant and tibial fractures occurring during preparation for the tibial keel and impaction of the tibial component. Conclusions Intra-operative fractures during primary total knee arthroplasty are rare with higher risk associated with osteoporosis, rheumatoid arthritis, advanced age, female gender, chronic steroid use, metabolic bone disorders, PS type of femoral implant and difficult surgical exposure of the knee joint due to severe deformities. A plethora of management options have been utilized according to surgeon preference. Standard principles of fracture fixation and arthroplasty principles should be followed to achieve stable internal fixation and any unstable fracture site should be bypassed with the utilization of stemmed components. Satisfactory radiographic and functional outcome can be expected with appropriate treatment.

Prevalence of osteoporosis and osteopenia in elderly patients scheduled for total knee arthroplasty

“…Owing to the considerable risk of osteoporosis in elderly patients with OA [8][9][10], the International Society for Clinical Densitometry (ISCD) recommends an assessment of bone mineral density (BMD) in women aged ≥ 65 years and men aged ≥ 70 years prior to orthopedic surgery, including TKA, to avoid adverse outcomes [11]. In TKA, poor bone status has been associated with intraoperative and periprosthetic fractures, migration of components, and aseptic loosening [12][13][14][15][16]. Furthermore, decreased BMD in the proximal tibia has been identified as a risk factor for Maximilian M. Delsmann and Constantin Schmidt contributed equally to this work.…”

Tibial periprosthetic fractures in Total Knee Arthroplasty – A scoping review

“…6,7 Intraoperative fractures amount to approximately 0.2%e4.4% of the cases. 8,9 Several risk factors have been identified that compromise bone quality and are responsible for PPFxs, such as osteoporosis, older age and prolonged steroid use, 10 female gender, medical comorbidities like Diabetes, 11 Rheumatologic diseases, 12 and Metabolic diseases. 2,10 It has been documented that during or after TKA, females are 2.3e4.4 times more likely than males to sustain PPFxs.…”

Intraoperative Fractures of the Tibia and Femur in Knee Revision Surgery

“…Intra-operative fractures have a low prevalence in primary arthroplasty, ranging from 0.2 % to 2.2 % [1]. They mainly occur during the preparation and implantation of the prosthesis.…”

“…The prevalence of intra-operative fractures of the knee joint in revision surgery is slightly higher, ranging from 3 % to 4.5 % [1]. In addition to metaphyseal fractures, diaphyseal fractures also occur during revision surgery, especially when using non-cemented stems.…”