Intra-operative forecasting of growth modulation spine surgery outcomes with spatio-temporal dynamic networks

Mandel, William J.; Parent, Stefan; Kadoury, Samuel

doi:10.1007/s11548-021-02461-7

Cited by 2 publications

(1 citation statement)

References 23 publications

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“…Mandel et al [23][24][25] published a series of studies on the use of statistical and machine learning models for predicting the surgical outcomes of Anterior Vertebral Body Tethering (AVBT) procedures in adolescents with idiopathic scoliosis. They developed statistical frameworks and predictive networks that use 3D spine reconstructions from follow-up radiographs to predict the surgical outcomes of AVBT.…”

Section: Introductionmentioning

confidence: 99%

Predicting radiographic outcomes of vertebral body tethering in adolescent idiopathic scoliosis patients using machine learning

Alfraihat,

Samdani,

Balasubramanian

2024

PLoS ONE

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Anterior Vertebral Body Tethering (AVBT) is a growing alternative treatment for adolescent idiopathic scoliosis (AIS), offering an option besides spinal fusion. While AVBT aims to correct spinal deformity through growth correction, its outcomes have been mixed. To improve surgical outcomes, this study aimed to develop a machine learning-based tool to predict short- and midterm spinal curve correction in AIS patients who underwent AVBT surgery, using the most predictive clinical, radiographic, and surgical parameters. After institutional review board approval and based on inclusion criteria, 91 AIS patients who underwent AVBT surgery were selected from the Shriners Hospitals for Children, Philadelphia. For all patients, longitudinal standing (PA or AP, and lateral) and side bending spinal Radiographs were retrospectively obtained at six visits: preop and first standing, one year, two years, five years postop, and at the most recent follow-up. Demographic, radiographic, and surgical features associated with curve correction were collected. The sequential backward feature selection method was used to eliminate correlated features and to provide a rank-ordered list of the most predictive features of the AVBT correction. A Gradient Boosting Regressor (GBR) model was trained and tested using the selected features to predict the final correction of the curve in AIS patients. Eleven most predictive features were identified. The GBR model predicted the final Cobb angle with an average error of 6.3 ± 5.6 degrees. The model also provided a prediction interval, where 84% of the actual values were within the 90% prediction interval. A list of the most predictive features for AVBT curve correction was provided. The GBR model, trained on these features, predicted the final curve magnitude with a clinically acceptable margin of error. This model can be used as a clinical tool to plan AVBT surgical parameters and improve outcomes.

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Section: Introductionmentioning

confidence: 99%

Predicting radiographic outcomes of vertebral body tethering in adolescent idiopathic scoliosis patients using machine learning

Alfraihat,

Samdani,

Balasubramanian

2024

PLoS ONE

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Applications of artificial intelligence for adolescent idiopathic scoliosis: mapping the evidence

Goldman,

Hui,

Choi

et al. 2024

Spine Deform

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Purpose Adolescent idiopathic scoliosis (AIS) is a common spinal deformity with varying progression, complicating treatment decisions. Artificial intelligence (AI) and machine learning (ML) are increasingly prominent in orthopedic care, aiding in diagnosis, risk-stratification, and treatment guidance. This scoping review outlines AI applications in AIS. Methods This study followed PRISMA-ScR guidelines and included articles that reported the development, use, or validation of AI models for treating, diagnosing, or predicting clinical outcomes in AIS. Results 40 full-text articles were included, with most studies published in the last 5 years (77.5%). Common ML techniques were convolutional neural networks (55%), decision trees and random forests (15%), and artificial neural networks (15%). Most AI applications in AIS were for imaging analysis (25/40; 62.5%), focusing on automatic measurement of Cobb angle, and axial vertebral rotation (13/25; 52%) and curve classification/severity (13/25; 52%). Prediction was the second most common application (15/40; 37.5%), with studies predicting curve progression (9/15; 60%), and Cobb angles (9/15; 60%). Only 15 studies (37.5%) reported clinical implementation guidelines for AI in AIS management. 52.5% of studies reported model accuracy, with an average of 85.4%. Conclusion This review highlights the applications of AI in AIS care, notably including automatic radiographic analysis, curve type classification, prediction of curve progression, and AIS diagnosis. However, the current lack of clear clinical implementation guidelines, model transparency, and external validation of studied models limits clinician trust and the generalizability and applicability of AI in AIS management.

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Intra-operative forecasting of growth modulation spine surgery outcomes with spatio-temporal dynamic networks

Cited by 2 publications

References 23 publications

Predicting radiographic outcomes of vertebral body tethering in adolescent idiopathic scoliosis patients using machine learning

Predicting radiographic outcomes of vertebral body tethering in adolescent idiopathic scoliosis patients using machine learning

Applications of artificial intelligence for adolescent idiopathic scoliosis: mapping the evidence

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