2012
DOI: 10.4187/respcare.01527
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Intra-individual Variation of the Cuff-Leak Test as a Predictor of Post-Extubation Stridor

Abstract: The intra-individual variation of CLT immediately post-intubation and pre-extubation does not improve the accuracy of a standard pre-extubation CLT to predict post-extubation stridor. Moreover, the standard pre-extubation CLT did not appear in our study to be an ideal test to detect post-extubation stridor. Larger studies should be performed before generalizing these preliminary results.

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Cited by 26 publications
(31 citation statements)
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“…Even though Gros et al 9 reported a sensitivity of 86% in their study results, the wide confidence intervals (95% CI 42-100%), and the results of other studies point to an overall low sensitivity of cuff leak volumes in detecting post-extubation stridor. While there is currently no evidence that delaying extubation of patients with a positive CLT improves outcomes, the following considerations can help to reduce the incidence of extubation failure and improve the success rate of reintubation attempts…”
Section: See the Original Study On Page 2026mentioning
confidence: 61%
See 1 more Smart Citation
“…Even though Gros et al 9 reported a sensitivity of 86% in their study results, the wide confidence intervals (95% CI 42-100%), and the results of other studies point to an overall low sensitivity of cuff leak volumes in detecting post-extubation stridor. While there is currently no evidence that delaying extubation of patients with a positive CLT improves outcomes, the following considerations can help to reduce the incidence of extubation failure and improve the success rate of reintubation attempts…”
Section: See the Original Study On Page 2026mentioning
confidence: 61%
“…9 They performed the CLT (as proposed by Miller and Cole) immediately after intubation (T0) and before extubation (T1) to evaluate the differences in cuff leak: ⌬CLT ϭ CLT1 -CLT0. A positive CLT was defined as ⌬CLT Ͻ 0 mL, according to the receiver-operating characteristic curve.…”
mentioning
confidence: 99%
“…One significant problem of the cuff‐leak test is that it is a ‘snap shot’ of a dynamic process – laryngeal oedema. The potential variability in laryngeal oedema over time may confound the results of standard pre‐extubation cuff‐leak testing . It is, therefore, a test that should be used only as part of a dynamic management plan, including other tests such as visualisation of the larynx, as well as a planned re‐intubation protocol.…”
Section: Resultsmentioning
confidence: 99%
“…Patients were tested in the operating room after general anesthesia and endotracheal intubation Six respiratory cycles were observed until equalization between inspired and expired tidal volumes took place, with an acceptable error margin of 20 mL 5,14 . After adequate suctioning, the ETT cuff was then deflated and then two additional respiratory cycles were performed to allow the subject to cough.…”
Section: Clt Testing Protocolmentioning
confidence: 99%