“…19 Although radial nerve blockade, as described by Bhakta and Zaheer, 1 is a relatively simple solution to arterial linerelated RAS, an effective treatment may also be achieved with intra-arterial injection of vasodilators. 20 Not surprisingly, neither of these strategies has been subjected to rigorous scientific scrutiny as to their effectiveness, duration of action, etc. Moreover, while it seems plausible that arterial cannula-related RAS can be a precursor to thrombosis, ischemia, and ultimately target organ damage, 21 the nature of this relationship and the confounding effects of patient comorbidities and clinical circumstances (e.g., hypothermia, excessive blood loss, hypotension, etc.)…”