Intra-Arterial Chemotherapy for the Treatment of Liver Metastases from Colorectal Cancer

Milandri, Carlo; Calzolari, Filippo; Giampalma, Emanuela; Passardi, Alessandro; Monti, Maria; Maltoni, Marco; Golfieri, Rita; Amadori, Dino

doi:10.1177/030089160208800456

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2008

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“…HAI plus systemic chemotherapy has been associated with response rates of 60-90% for unresectable CLM, even in the second and third line settings, with conversion to resectability in up to 35% of patients [3,4,[15][16][17][18]. Critics of this approach cite a significant incidence of short-and long-term complications, including complications related to the pump itself and biliary sclerosis, which is reversible if recognized in its early stages but can lead to stricture and liver failure.…”

Section: Discussionmentioning

confidence: 99%