Intra‐arterial angiolymphoid hyperplasia with eosinophilia

Koubaa, Wafa; Verdier, M.; Perez, Michael A.; Wechsler, Janine

doi:10.1111/j.1600-0560.2007.00837.x

Cited by 25 publications

(12 citation statements)

References 23 publications

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“…Histopathologically, ALHE shows a vascular proliferation of small vessels lined by plump endothelial cells, often accompanied by inflammatory infiltrates with numerous eosinophils and lymphocytes (1). The pathogenesis of ALHE is proposed as a neoplastic process, hypersensitivity reaction, inflammatory vascular reaction or tissue reaction to a previous trauma.…”

Section: Diagnosis: Angiolymphoid Hyperplasia With Eosinophiliamentioning

confidence: 99%

“…Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare angioproliferative disorder of unknown origin, characterized by solitary or multiple, usually 0.5-3 cm diameter, red-to-brown dome-shaped subcutaneous nodules, usually occurring on the head and neck, particularly in the auricular and periauricular areas, and very rarely on the extremities and trunk (1,2). Histopathologically, ALHE shows a vascular proliferation of small vessels lined by plump endothelial cells, often accompanied by inflammatory infiltrates with numerous eosinophils and lymphocytes (1).…”

Section: Diagnosis: Angiolymphoid Hyperplasia With Eosinophiliamentioning

confidence: 99%

See 1 more Smart Citation

Erythematous Protruding Skin Lesion in the Retroauricular Area: A Quiz

Jung

Kim²,

Lee³

et al. 2014

Acta Derm Venerol

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A 31-year-old Korean man presented with an asymptomatic, easy-to-bleed, solitary, rapidly enlarging, and erythematous protruding skin lesion with a stalk on the posterior auricular area, which he had first noticed 6-7 weeks prior to visiting our clinic (Fig. 1). In June 2010, the patient had been diagnosed with chronic myelogenous leukaemia, which was treated first with hydroxyurea and, since September 2012, had been managed with oral radotinib, 600 mg/day. The patient had no history of trauma and denied any family history of similar skin lesions. Our initial impression was pyogenic granuloma or accessory tragus. A skin biopsy showed a proliferation of small-to-medium-sized blood vessels with a cobblestone appearance of enlarged endothelial cells that projected into the lumina. A perivascular inflammatory cell infiltrate was composed mainly of lymphocytes and eosinophils (Fig. 2). The lesion has not recurred during 1-year follow-up after excision and electrodessication. Fig. 2. Cobblestone appearance of enlarged endothelial cells that projected into the lumina, and perivascular inflammatory cell infiltrates composed mainly of lymphocytes and eosinophils (haematoxylin and eosin; × 400).

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Section: Diagnosis: Angiolymphoid Hyperplasia With Eosinophiliamentioning

confidence: 99%

Section: Diagnosis: Angiolymphoid Hyperplasia With Eosinophiliamentioning

confidence: 99%

Erythematous Protruding Skin Lesion in the Retroauricular Area: A Quiz

Jung

Kim²,

Lee³

et al. 2014

Acta Derm Venerol

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show abstract

“…The latter appeared as a vascular tumor with aneurysmal dilatation of the radial artery. 1,2 To our knowledge, this is the first described case of simultaneous presentation of skin and vascular lesions in extremities, extending the spectrum of clinical presentation of this rare disease.…”

Section: Alhe Is a Rare Benign Disorder First Published By Wells Andmentioning

confidence: 99%

“…It is known by different names, even sometimes confused with Kimura's disease (KD). [1][2][3] The clinical presentation is variable, usually single lesions located in the head or the neck, and less frequently in the trunk, groin or limbs for which it has always been described as a single injury. It often affects skin and subcutaneous tissue, but vascular lesions have been described.…”

Section: Introductionmentioning

confidence: 99%

Angiolymphoid hyperplasia with eosinophilia as simultaneous cutaneous and vascular lesions with radial artery aneurysm

et al. 2016

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“…The common features of these entities are nodules in the head and neck adjacent or within the vasculature. 1 Epidemiological differences between the 3 exist but partially overlap or are inconsistent in the literature. Angiolymphoid dysplasia with eosinophilia often occurs in young women in the third and fourth decade with multiple lesions, no regional lymphadenopathy, mild eosinophilia and immunoglobulin E elevation, arteriovenous malformations from exuberant angiomatoid proliferation, and masses of uncanalized epitheloid or histiocytoid endothelial cells.…”

mentioning

confidence: 99%