Intra and latero-sellar carotid aneurysm mimicking a pituitary adenoma

Bouznad, N.; Ansari, N. El

doi:10.11604/pamj.2015.22.150.8043

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Ряд проведенных исследований [11][12][13][14][15] продемонстрировал нарушения секреции гормонов гипофиза при компрессии СГ различными объемными образованиями ХСО, такими как АГ, менингиомы, КФ, герминомы, глиомы, воспалительные процессы (туберкулез, саркоидоз), метастазы, аневризмы сонной артерии. Пациенты с компрессией СГ и портальных сосудов имеют умеренную гиперпролактинемию и снижение секреции гипофизарных гормонов.…”

Section: Discussionunclassified

Preoperative and postoperative endocrine disorders associated with pituitary stalk injuries caused by suprasellar growing tumors

et al. 2018

View full text Add to dashboard Cite

Given the difference in symptoms associated with compression and surgical transection of the PS, we believe that these two concepts should be clearly distinguished. The PS compression syndrome includes primarily hyperprolactinemia (37% of cases); elimination of PS compression leads to normalization of the PRL level in most patients and is not accompanied by aggravation of hypopituitarism symptoms. The PS transection syndrome in patients with CP and HIA led to the development of panhypopituitarism in all patients and permanent diabetes insipidus in most of them. The causes of the absence of hyperprolactinemia in many patients with PS transection require further research. The surgeon planning intraoperative PS transection to increase the radicality of surgery should be well informed about the consequences of this procedure for the patient's endocrine status.

show abstract

Section: Discussionunclassified

Preoperative and postoperative endocrine disorders associated with pituitary stalk injuries caused by suprasellar growing tumors

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Проведенные исследования [11][12][13][14][15] демонстрируют нарушения секреции гормонов гипофиза при компрессии СГ объемным процессом в ХСО, таким как макроаденомы гипофиза, менингиомы, КФ, герминомы, глиомы, воспалительные процессы (туберкулез, саркоидоз), метастазы, аневризмы сонной артерии. Пациенты с компрессией портальных сосудов имеют умеренную гиперпролактинемию и снижение секреции гипофизарных гормонов.…”

unclassified

Clinical syndromes of compression and surgical transection of the pituitary stalk

Astafyeva

Кадашев

Kalinin

et al. 2018

Probl Endokrinol (Mosk)

View full text Add to dashboard Cite

Background. The pituitary stalk (PS) is an anatomical structure consisting of the portal vessel system and axons of the hypothalamic nuclei terminating in the posterior pituitary lobe. Surgical injury or compression (by a tumor or another space-occupying process) of the PS can lead to hypopituitarism, diabetes insipidus, and hyperprolactinemia. However, the literature lacks studies on the extent of these disorders depending on PS injury or compression in clinical practice. Aim. The study aim was to investigate pre- and postoperative endocrine disorders in patients with chiasmo-sellar region (CSR) tumors and the PS compressed and preserved or involuntarily transected during neurosurgery. Material and methods. The PS compressed before surgery was preserved in 82 patients (41 patients with non-functioning endosuprasellar adenoma and 41 — with suprasellar meningioma). The PS was transected during transcranial surgery in 57 patients (46 patients with pituitary stalk craniopharyngioma and 11 patients with non-functioning endosupresellar pituitary adenoma). All patients underwent blood tests for prolactin (PRL), TSH, LH, FSH, free T4, cortisol, testosterone, or estradiol levels before and 6 months after surgery. Results. Hyperprolactinemia was detected in 37.4% of patients with CSR tumors compressing the PS. Elimination of PS compression led to normalization of the PRL level in most patients and was not accompanied by worsening of hypopituitarism symptoms. Transection of the PS resulted in panhypopituitarism in 100% of patients and diabetes insipidus in 93% of cases. There was no evidence of hyperprolactinemia in 58.7% of patients with craniopharyngiomas and 81.9% of patients with non-functioning pituitary adenomas. Conclusion. Given the difference in symptoms, we distinguished two syndromes: PS compression syndrome and PS transection syndrome. Syndrome of PS compression by a CSR tumor was characterized mainly by hyperprolactinemia (37.4% of cases); elimination of PS compression due to tumor resection led to normalization of the PRL level in most patients and was not accompanied by worsening of hypopituitarism symptoms. Syndrome of surgical PS transection in patients with craniopharyngioma (CP) and non-functioning pituitary adenoma (NFPA) manifested as panhypopituitarism in all patients and as permanent diabetes insipidus in most of them. The causes for the absence of hyperprolactinemia in many patients with the transected PS require further research. We can not exclude both adenohypophysis ischemia (due to its impaired blood supply) with partial or complete atrophy of lactotrophic cells and pituitary revascularization with restoration of dopamine transport.

show abstract

Intra and latero-sellar carotid aneurysm mimicking a pituitary adenoma

Cited by 2 publications

References 0 publications

Preoperative and postoperative endocrine disorders associated with pituitary stalk injuries caused by suprasellar growing tumors

Preoperative and postoperative endocrine disorders associated with pituitary stalk injuries caused by suprasellar growing tumors

Clinical syndromes of compression and surgical transection of the pituitary stalk

Contact Info

Product

Resources

About