Intra- and extracranial artery blood velocity during a sudden blood pressure decrease in humans

Savin, E.; Siègelovà, Jarmila; Fisher, Brandon; Bonnin, Philippe

doi:10.1007/s004210050250

Cited by 5 publications

(2 citation statements)

References 33 publications

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“…In the phantom, the flow velocity changed from 0 to 80.39 cm/sec; for instance, in the common carotid artery, the velocity is 22.28 cm/s [ 19 , 20 ].…”

Section: Methodsmentioning

confidence: 99%

The Direction of Flow and Phase-encoding Schemes Effects on Signal Intensity in T1-weighted Inversion Recovery TurboFLASH Images

Nazarpoor

2023

J Biomed Phys Eng

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Background: It is needed to minimize the effect of flow direction on the desired area, such as arterial input function (AIF) in magnetic resonance imaging (MRI). Objective: The current study aimed to investigate the effect of flow direction on different velocities (0–80.39 cm/s) for the strength of the signal intensity (SI) at the linear phase-encoding (LPE) and the center out phase-encoding (COPE) schemes and to recommend the best flow direction in a selected slice and scheme for absolute perfusion measurement by inversion recovery T1-weighted turbo fast low-angle shot (TurboFLASH) MR images. Material and Methods: In this experimental study, the flow rates were measured using a flow phantom, and the signal intensity (SI) was measured at the two opposite flow directions in the Z-axis perpendicular to the coronal image at a concentration of 0.8 mmol/L of gadolinium-diethylenetriaminepantaacetic acid (Gd-DTPA) by using the LPE and COPE schemes. Results: The increase in velocity along with the growth in SI and inflow affected the use of LPE and COPE acquisitions in both directions. The velocity of the arterial input function is needed to calculate the inflow correction factor by using two schemes in two opposite flow directions to investigate perfusion. Conclusion: The COPE scheme was better than the LPE scheme in measuring perfusion since the velocity and direction of blood flow affect SI less.

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“…In the phantom, the flow velocity changed from 0 to 80.39 cm/sec; for instance, in the common carotid artery, the velocity is 22.28 cm/s [ 19 , 20 ].…”

Section: Methodsmentioning

confidence: 99%

The Direction of Flow and Phase-encoding Schemes Effects on Signal Intensity in T1-weighted Inversion Recovery TurboFLASH Images

Nazarpoor

2023

J Biomed Phys Eng

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“…However, more recent work suggests that the vascular bed of the ECA is not regulated by sympathetic activity and does not contribute to CBF regulation during acute hypotension in healthy young men [4]. Previous experiments similarly suggested that the extracranial vasculature is passive [11].…”

Section: Introduction and Motivationsmentioning

confidence: 99%

Cerebral hemodynamics: a mathematical model including autoregulation, baroreflex and extracranial peripheral circulation

Linninger

2021

Preprint

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Increasing evidence supports that cerebral autoregulation and mean arterial pressure regulation via baroreflex contribute to cerebral blood flow regulation. It is unclear whether the extracranial vascular bed of the head and neck helps reestablishing cerebral blood flow during changes in mean arterial pressure. Current computational models of cerebral blood flow regulation do not address the relationships between the intracranial and extracranial blood flow dynamics. We present a model of cerebral autoregulation, extracranial peripheral circulation and baroreflex control of heart rate and of peripheral vasculature that was included to the model of intracranial dynamics proposed by Linninger et al. (2009), which incorporates the fully coupled blood, cerebrospinal fluid and brain parenchyma systems. Autoregulation was modelled as being pressure-mediated at the arteries and arterioles and flow-mediated at the microcirculation. During simulations of a bout of acute hypotension, cerebral blood flow returns rapidly to baseline levels with a very small overshoot, whereas the blood flow to the peripheral circulation of the head and neck suffers a prolonged suppression in accordance with experimental evidence. The inclusion of baroreflex regulation at the extracranial vascular bed had a negligible effect on cerebral blood flow regulation during dynamic changes in mean arterial pressure. Moreover, the results suggest that the extracranial blood flow carries only modest information about cerebral blood flow in dynamic situations in which cerebral autoregulation is preserved and mean arterial pressure suffers alterations. This information is likely higher when the autoregulation is impaired. Steady-state cerebral blood flow in the model is kept within normal ranges despite variations in mean arterial pressure from 50 to 175 mmHg. By inputting aortic pressure waves from individuals with increasing arterial rigidity, increasing arterial systolic and pulse pressures, the model predicts the generation of intracranial pressure waves with accordingly increasing peaks and amplitudes.

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Analysis of Hemodynamic Changes in Early Stage after Carotid Stenting by Transcranial Doppler—A Preliminary Study

Zhang

Yang

Niu

et al. 2017

Annals of Vascular Surgery

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Intra- and extracranial artery blood velocity during a sudden blood pressure decrease in humans

Cited by 5 publications

References 33 publications

The Direction of Flow and Phase-encoding Schemes Effects on Signal Intensity in T1-weighted Inversion Recovery TurboFLASH Images

The Direction of Flow and Phase-encoding Schemes Effects on Signal Intensity in T1-weighted Inversion Recovery TurboFLASH Images

Cerebral hemodynamics: a mathematical model including autoregulation, baroreflex and extracranial peripheral circulation

Analysis of Hemodynamic Changes in Early Stage after Carotid Stenting by Transcranial Doppler—A Preliminary Study

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