Intra-abdominal hypertension and abdominal compartment syndrome

Waele, Jan J. De

doi:10.1097/mcc.0000000000000991

Cited by 3 publications

(2 citation statements)

References 61 publications

(65 reference statements)

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“…While many attempts have been made to improve and/or simplify IAP measurement, research has shown that none of these novel techniques is truly superior to the standard, transvesical route. Additionally, biomarkers and imaging have also been tested, which were also not ready to replace traditional IAP measurement for the diagnosis of IAH or ACS [ 6 ]. Current treatment guidelines remain largely unchanged, with nonoperative management options as the preferred strategy for most patients.…”

Section: Discussionmentioning

confidence: 99%

An Extreme Case of Lethal Abdominal Compartment Syndrome in Pediatric Patient With Synovial Sarcoma

Zhang¹,

Saliba²,

Sobrino³

et al. 2023

Cureus

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There is a relative paucity of literature on abdominal compartment syndrome (ACS) in children compared to adults and even less describing ACS in pediatric oncologic patients. We present this case of ACS in a 14-yearold patient to highlight the acuity of lethal consequences despite swift adequate management. Our patient is a 14-year-old male with a history of non-verbal autism and large synovial sarcoma of the left chest wall. He was admitted for scheduled inpatient chemotherapy and radiation. On day 3 of admission, the patient's clinical condition rapidly deteriorated, and a surgical abdomen was found on the exam. In the operating room (OR), massive gaseous distention of the stomach, small intestines, and colon were noted. A loop of small bowel was under such high pressure that the force of evisceration sheared the bowel from the associated mesentery. Due to the severity of the dilated bowel loops, we could not return the eviscerated bowel back inside the abdomen, which led us to leave the Abthera wound vac as sole coverage. The patient was transferred to the PICU, and medical treatment was aimed toward palliative care. The patient passed away three hours later. This case illustrates the acute and lethal nature of ACS in a less studied population, the pediatric oncologic patient. Prompt detection and treatment of ACS are essential for the management of critically ill pediatric patients, especially in those with space occupying tumors within the abdominal cavity. However, extreme presentations of ACS can have lethal consequences despite swift surgical intervention and adequate management.

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Section: Discussionmentioning

confidence: 99%

An Extreme Case of Lethal Abdominal Compartment Syndrome in Pediatric Patient With Synovial Sarcoma

Zhang¹,

Saliba²,

Sobrino³

et al. 2023

Cureus

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“…Further studies showed that the activated. [27] renin-angiotensin system (RAS) increased significantly, renal resistance increased and glomerular filtration decreased in SAP patients with hypotension and hypovolemia. [28,29]…”

Section: Complications Of Abdominal Compartment Syndromementioning

confidence: 99%

Progress in Pathogenesis of Pancreatitis with Acute Kidney Injury

Hu,

Zhou

2024

J Clin Med Res

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Acute pancreatitis (AP) is a common gastrointestinal disease. About 20% of patients with acute pancreatitis develop severe acute pancreatitis, often with multiple organ dysfunction and poor prognosis. In the process, about 10% of patients develop acute renal injury (AKI). Acute renal injury (AKI) is a major complication of severe pancreatitis with a case fatality rate of up to 75%. AP associated AKI (AP-AKI) has both common and significant differences from other AKIs associated with intensive care. Although its pathogenesis is not clear, systemic and regional inflammatory responses play a key role. Early detection, early and effective support and pathogen treatment can significantly improve the results.

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