Intra-abdominal abscesses by Lactococcus lactis ssp cremoris in an immunocompetent adult with severe periodontitis and pernicious anemia

Abstract

We report the case of an immunocompetent man who presented with fever and abdominal pain and was found to have a hepatic abscess and a peri-renal abscess with a computerized tomography scan. The hepatic abscess was drained percutaneously and cultures revealed the presence of Lactococcus lactis that was sensitive to penicillin. The patient was successfully treated with ceftriaxone and metronidazole with resolution of the abscesses. Further work-up revealed atrophic gastritis, vitamin B12 deficiency, periodontitis and gingivitis, suggesting a possible site of entry for the development of the abscesses.

Lactococcus lactis cremoris intra-uterine infection: About an uncommon case report

“…Therefore, its pathogenic potential is becoming well known by the scientific community. To our knowledge, our case is the second published case of Lactococcus lactis cremoris IUI and the 27th worldwide for other infectious sites [4] , [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] . Indeed, a review of the literature ( Table 1 ) allowed us to find the 26 cases published before ours and allowed us to highlight some of the features of this uncommon infection.…”

“…It is interesting to note that all the antibiotic susceptibility tests that were reported in the literature were in line with a bacterial sensitivity to penicillin and other families of antibiotics, namely aminoglycosides and glycopeptides. Although antibiotic regimens based on the result of susceptibility tests are the mainstay of treatment, fifteen cases (56%), including ours, have reported the need for associated surgical management due to the severity of the abscess in relation to its location, to its size or even its compressive effect [4] , [7] , [8] , [10] , [11] , [12] , [13] , [14] , [16] , [18] , [21] , [22] , [24] , [25] .…”

“…Therefore, we chose to include them in cases of compromised immunity. Pregnancy was reported in 7% of cases whereas history of oro-dental pathologies has been found in 30% of cases [8] , [12] , [17] , [19] , [20] , [21] , [24] , [31] . Nonetheless, the most significant risk factor remains the consumption of unpasteurized dairy products, which was found in 52% of patients, including ours [7] , [8] , [9] , [10] , [13] , [17] , [18] , [21] , [23] , [27] , [28] , [30] , [31] .…”

“…Regarding pathophysiology, the mode of invasion was most often considered to be hematogenous (88%) as in the seven cases reported of endocarditis [15] , [17] , [20] , [23] , [26] , [29] , [31] , the five cases of nervous system infection [7] , [11] , [12] , [13] , [24] , the five cases of hepatobiliary system infection [8] , [14] , [16] , [22] , [25] , the three cases of pleuropulmonary infection [9] , [18] , [30] , the first case of IUI [4] as well as in the cases of articular infection [28] , ocular infection [19] and septicemia [27] . But it could also occur by loco-regional spread as in the two cases of cervical soft tissue abscesses from a potential oral site infection [10] , [21] .…”

La microbiota según la topografía gástrica en pacientes con bajo y con alto riesgo de cáncer gástrico en Nariño, Colombia

“…Lactococcus lactis es una bacteria de uso en la industria láctea cuya presencia en individuos con cáncer gástrico incrementa ( 27) y que se asocia con otros tipos de malignidad en pacientes inmunocomprometidos (28). El papel del lactato potencia la inflamación y su producción aumenta en el metabolismo de las células cancerígenas (29,30).…”