Intoxication au plomb chez la femme enceinte et le nouveau-né: bilan d'une enquête de dépistage

Yazbeck, Chadi; Cheymol, J; Dandres, Anne-Marie; Barbery-Courcoux, A.-L.

doi:10.1016/j.arcped.2006.09.016

Cited by 26 publications

(5 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The cord blood lead levels found in our study were similar to those observed in newborns from other European countries during the same period [31,32], with only one child showing lead concentrations above the present CDC reference level of 50 μg/L (CDC., 2012). A previous study in the Spanish city of Barcelona showed a reduction on cord blood lead concentrations from 186 μg/L in 1984 to 40.06 μg/L in 1995, parallel to the decrease in lead petrol concentrations in the ambient air [33].…”

Section: Discussionsupporting

confidence: 88%

Lead, mercury and cadmium in umbilical cord blood and its association with parental epidemiological variables and birth factors

et al. 2013

View full text Add to dashboard Cite

BackgroundIn Spain, few studies have evaluated prenatal exposure to heavy metals. The objective of this study was to describe lead, mercury and cadmium concentrations in blood from a sample of newborn–mother-father trios, as well as to investigate the association between metals in cord blood and parental variables. We also explored the relationship between cord blood metal concentrations and child characteristics at birth.MethodsMetal correlations among family members were assessed using Spearman Rank Correlation Coefficient. Linear regression was used to explore the association between parental variables and log-transformed cord blood lead and cord blood mercury concentrations. In the case of cadmium, tobit regression was used due to the existence of samples below the detection limit. The association between cord blood metal concentrations and child characteristics at birth was evaluated using linear regression.ResultsGeometric means for lead, mercury and cadmium were 14.09 μg/L, 6.72 μg/L and 0.27 μg/L in newborns; 19.80 μg/L, 3.90 μg/L and 0.53 μg/L in pregnant women; and 33.00 μg/L, 5.38 μg/L and 0.49 μg/L in men. Positive correlations were found between metal concentrations among members of the trio. Lead and cadmium concentrations were 15% and 22% higher in newborns from mothers who smoked during pregnancy, while mercury concentrations were 25% higher in newborns from mothers with greater fish intake. Cord-blood lead levels showed seasonal periodicity, with lower concentrations observed in winter. Cord blood cadmium concentrations over 0.29 μg/L were associated with lower 1-minute and 5-minute Apgar scores.ConclusionsThese results reinforce the need to establish biomonitoring programs in Spain, and provide support for tobacco smoke and fish consumption as important preventable sources of heavy metal exposure in newborns. Additionally, our findings support the hypothesis that cadmium exposure might be deleterious to fetal development.

show abstract

Section: Discussionsupporting

confidence: 88%

Lead, mercury and cadmium in umbilical cord blood and its association with parental epidemiological variables and birth factors

et al. 2013

View full text Add to dashboard Cite

show abstract

“…For example, a study from Belgium reported cord blood arithmetic mean lead concentration of 1.5 μg/dL [ 61 ]. Two separate studies from France reported cord blood arithmetic mean lead concentrations of 1.5 μg/dL [ 62 , 63 ] and 2.3 μg/dL [ 62 , 63 ]. A study from Canada reported cord blood arithmetic mean lead concentration of 2.8 μg/dL [ 64 ], and another study from Saudi Arabia reported cord blood arithmetic mean lead concentration of 2.5 μg/dL [ 65 ].…”

Section: Discussionmentioning

confidence: 99%

Concentration of Lead, Mercury, Cadmium, Aluminum, Arsenic and Manganese in Umbilical Cord Blood of Jamaican Newborns

Rahbar

Samms‐Vaughan

Dickerson

et al. 2015

IJERPH

View full text Add to dashboard Cite

The objective of this study was to characterize the concentrations of lead, mercury, cadmium, aluminum, and manganese in umbilical cord blood of Jamaican newborns and to explore the possible association between concentrations of these elements and certain birth outcomes. Based on data from 100 pregnant mothers and their 100 newborns who were enrolled from Jamaica in 2011, the arithmetic mean (standard deviation) concentrations of cord blood lead, mercury, aluminum, and manganese were 0.8 (1.3 μg/dL), 4.4 (2.4 μg/L), 10.9 (9.2 μg/L), and 43.7 (17.7 μg/L), respectively. In univariable General Linear Models, the geometric mean cord blood aluminum concentration was higher for children whose mothers had completed their education up to high school compared to those whose mothers had any education beyond high school (12.2 μg/L vs. 6.4 μg/L; p < 0.01). After controlling for maternal education level and socio-economic status (through ownership of a family car), the cord blood lead concentration was significantly associated with head circumference (adjusted p < 0.01). Our results not only provide levels of arsenic and the aforementioned metals in cord blood that could serve as a reference for the Jamaican population, but also replicate previously reported significant associations between cord blood lead concentrations and head circumference at birth in other populations.

show abstract

“…Водночас на тлі активної внутрішньо-і трансплацентарної міграції ксенобіотиків відбувається порушення процесів транслокації есенціальних мікроелементів із організму матері до плоду, які характеризуються досить низькою здатністю до проникнення у кров плоду -0,52-0,65 ум.од., що зумовлює зменшення у даному біосубстраті вмісту низки мікроелементів -міді, кобальту, марганцю у 1,7-3,1 рази, цинку та заліза -у 2,0-24,0 рази, що свідчить про розвиток цинк-та залізодефіцитних станів плодів 20-ти тижнів гестації. Вищенаведене, ймовірно, зумовлене фізіологічною незрілістю фетоплацентарного бар'єру на даний термін гестації плоду [9], коли токсиканти можуть навіть шляхом простої дифузії проникати через плаценту і, таким чином, мімікрують біогенні елементи, тобто незрілий плід вважає їх життєво важливими і накопичує [1].…”

Section: Ecological and Hygienic Determination Of The Deterioration Ounclassified

Ecological and hygienic determination of the deterioration of population’s health in the industrial region

Biletska¹,

Onul²,

Holovkova³

et al. 2016

Dovkil Zdor

View full text Add to dashboard Cite

Intoxication au plomb chez la femme enceinte et le nouveau-né: bilan d'une enquête de dépistage

Cited by 26 publications

References 11 publications

Lead, mercury and cadmium in umbilical cord blood and its association with parental epidemiological variables and birth factors

Lead, mercury and cadmium in umbilical cord blood and its association with parental epidemiological variables and birth factors

Concentration of Lead, Mercury, Cadmium, Aluminum, Arsenic and Manganese in Umbilical Cord Blood of Jamaican Newborns

Ecological and hygienic determination of the deterioration of population’s health in the industrial region

Contact Info

Product

Resources

About