Intimate behavior and allergy: a narrative review

Liccardi, Gennaro; Senna, Gianenrico; Rotiroti, Giuseppina; D’Amato, Gennaro; Passalacqua, Giovanni

doi:10.1016/s1081-1206(10)60562-5

Cited by 37 publications

(15 citation statements)

References 73 publications

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“…100,101 Unusual clinical presentations of CMA Unusual clinical presentations are as much a feature of CMA as one might expect from such a ubiquitous allergen source in food and the environment as milk (Box 1). [102][103][104][105][106][107][108][109][110][111][112] The natural history of CMA CMA is primarily of pediatric onset, [113][114][115] is generally outgrown, and is often the first stage of the ''allergic march.'' The take-home message about the latest developments regarding the natural history of CMA is reviewed in Table II.…”

Section: Epidemiology Of Cmamentioning

confidence: 99%

Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA): A summary report

Fiocchi¹,

Schünemann

Brožek

et al. 2010

Journal of Allergy and Clinical Immunology

243

220

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Section: Epidemiology Of Cmamentioning

confidence: 99%

Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA): A summary report

Fiocchi¹,

Schünemann

Brožek

et al. 2010

Journal of Allergy and Clinical Immunology

243

220

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“…There is also evidence that seminal fluid in humans can act as an allergen (Tomitaka et al , 2002; Guillet & Dagregorio, 2004). Human seminal plasma allergy (HSPA) is caused by local or systemic hypersensitivity to human semen (Liccardi et al , 2007). Reactions include local itching, burning, oedema, pain, blistering and systemic reactions include cough, rhinoconjunctivitis, nausea, vomiting, diarrhoea and anaphylaxis.…”

Section: The Evidence: Are Males Immunogenic To Females?mentioning

confidence: 99%

Female postmating immune responses, immune system evolution and immunogenic males

Morrow

Innocenti

2011

Biological Reviews

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Females in many taxa experience postmating activation of their immune system, independently of any genital trauma or pathogenic attack arising from male-female genital contact. This response has always been interpreted as a product of natural selection as it either prepares the female immune system for antigens arising from an implanted embryo (in the case of placental mammals), or is a "pre-emptive strike" against infection or injury acquired during mating. While the first hypothesis has empirical support, the second is not entirely satisfactory. Recently, studies that have experimentally dissected the postmating responses of Drosophila melanogaster females point to a different explanation: male reproductive peptides/proteins that have evolved in response to postmating male-male competition are directly responsible for activating particular elements of the female immune system. Thus, in a broad sense, males may be said to be immunogenic to females. Here, we discuss a possible direct role of sexual selection/sexual conflict in immune system evolution, in contrast to indirect trade-offs with other life-history traits, presenting the available evidence from a range of taxa and proposing ways in which the competing hypotheses could be tested. The major implication of this review is that immune system evolution is not only a product of natural selection but also that sexual selection and potentially sexual conflict enforces a direct selective pressure. This is a significant shift, and will compel researchers studying immune system evolution and ecological immunity to look beyond the forces generated by parasites and pathogens to those generated by the male ejaculate.

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“…Case reports have detailed the transfer of allergenic food protein through kissing and sexual intercourse, including cases of anaphylaxis. 12,13 Maloney et al 14 found that peanut allergen can remain in saliva for hours, even after tooth brushing or use of mouthwash, and was best removed after consumption of a nonpeanut meal. 14 In addition to impairing judgment, alcohol consumption can act as a cofactor for some food allergy reactions, either enhancing or contributing to the development of a reaction.…”

Section: Food Allergymentioning

confidence: 99%