Intestinal Transplant Registry Report: Global Activity and Trends

Grant, David; Abu‐Elmagd, Kareem; Mazariegos, George; Vianna, Rodrigo; Langnas, Alan Norman; Mangus, Richard S.; Farmer, Douglas G.; Lacaille, Florence; Iyer, Kishore; Fishbein, Thomas M.

doi:10.1111/ajt.12979

Cited by 396 publications

(322 citation statements)

References 62 publications

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“…posttransplant lymphoproliferative disorder [PTLD]) and graft and patient survival. We divided the posttransplant follow-up period into three intervals: early (first month), intermediate (months [1][2][3][4][5][6], and late (>6 months). All patients were followed up until July 2014, death or graft loss, whichever occurred first.…”

Section: Study Population and Designmentioning

confidence: 99%

Infectious Complications Following Small Bowel Transplantation

Silva

Juan

Fernández-Caamaño

et al. 2016

American Journal of Transplantation

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Microbiological spectrum and outcome of infectious complications following small bowel transplantation (SBT) have not been thoroughly characterized. We performed a retrospective analysis of all patients undergoing SBT from 2004 to 2013 in Spain. Sixty-nine patients underwent a total of 87 SBT procedures (65 pediatric, 22 adult). The median follow-up was 867 days. Overall, 81 transplant patients (93.1%) developed 263 episodes of infection (incidence rate: 2.81 episodes per 1000 transplant-days), with no significant differences between adult and pediatric populations. Most infections were bacterial (47.5%). Despite universal prophylaxis, 22 transplant patients (25.3%) developed cytomegalovirus disease, mainly in the form of enteritis. Specifically, 54 episodes of opportunistic infection (OI) occurred in 35 transplant patients. Infection was the major cause of mortality (17 of

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Section: Study Population and Designmentioning

confidence: 99%

Infectious Complications Following Small Bowel Transplantation

Silva

Juan

Fernández-Caamaño

et al. 2016

American Journal of Transplantation

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“…Intestinal rehabilitation has again gained popularity in recent years due to the questionable long term results of intestinal transplantation (56): since the '70 with the spreading of TPN, reports on surgical techniques of intestinal rescue after massive bowel resection have been published in the international literature. These procedures have been later ('90) partially abandoned with the upcoming beginning of the intestinal/multivisceral transplantation era, supported by new and powerful immunosuppressive drugs like FK 506.…”

Section: Discussionmentioning

confidence: 99%

Reconnection surgery in adult post-operative short bowel syndrome < 100 cm: is colonic continuity sufficient to achieve enteral autonomy without autologous gastrointestinal reconstruction? Report from a single center and systematic review of literature

Lauro¹

2017

GHIR

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“…Fig. 1 [19]. This is compared with an average of 238 isolated pancreas transplants and 750 combined kidney/pancreas (KP) transplant, for a total of just under 1000 pancreata transplanted per year.…”

Section: Intestine-based Grafts Excluding the Livermentioning

confidence: 99%

Should the Pancreas be Routinely Included with an Intestinal Graft?

2015

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Intestinal transplant is the only curative solution for children and adults with life-threatening complications of intestinal failure. A dilemma that arises often in real life, typically at the time of organ allocation involving multiple centers, is whether the pancreas can and/or should be procured and transplanted separately from an intestine-containing graft. Evidence appears to support routinely allocating the pancreas along with a composite liver-intestine graft. For all pediatric recipients and recipients of any age requiring foregut replacement, the pancreas would likewise seem fundamental to the graft. The only scenario where the pancreas might not be considered as integral to the graft is an isolated intestine transplant where the recipient does not require the foregut. We feel that the pancreas should generally be allocated with isolated intestine grafts in adults, as the added benefit to the pancreas recipient pool is not adequately offset by the risk to the intestine recipients.

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Intestinal Transplant Registry Report: Global Activity and Trends

Cited by 396 publications

References 62 publications

Infectious Complications Following Small Bowel Transplantation

Infectious Complications Following Small Bowel Transplantation

Reconnection surgery in adult post-operative short bowel syndrome < 100 cm: is colonic continuity sufficient to achieve enteral autonomy without autologous gastrointestinal reconstruction? Report from a single center and systematic review of literature

Should the Pancreas be Routinely Included with an Intestinal Graft?

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