Intestinal proteins synthesised in response to vitamin D

Spencer, Rosemary; Lawson, David; Charman, M.

doi:10.1007/bf02064037

Cited by 1 publication

(2 citation statements)

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“…It has been shown by several authors that vitamin d is required for calbindin d 28k synthesis in chicken. Chickens fed a low-Ca diet supplemented with adequate vitamin d concentrations had increased Ca absorption and calbindin d 28k expression [110]. In contrast, chicks that were raised on a vitamin d-deficient diet did not exhibit the same adaptation pattern to changes in dietary Ca concentration as those seen in chicks fed an adequate vitamin d diet [110]; similar results were observed by others [107,111].…”

Section: Calcium Homeostasissupporting

confidence: 80%

“…Chickens fed a low-Ca diet supplemented with adequate vitamin d concentrations had increased Ca absorption and calbindin d 28k expression [110]. In contrast, chicks that were raised on a vitamin d-deficient diet did not exhibit the same adaptation pattern to changes in dietary Ca concentration as those seen in chicks fed an adequate vitamin d diet [110]; similar results were observed by others [107,111]. Restrictions in dietary Ca and P in the presence of adequate vitamin d were characterized by an alteration in intestinal calbindin d 28k [111].…”

Section: Calcium Homeostasismentioning

confidence: 98%

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Calcium and phosphorus metabolism in broilers: Effect of homeostatic mechanism on calcium and phosphorus digestibility

Proszkowiec‐Weglarz

Angel

2013

Journal of Applied Poultry Research

163

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Calcium and phosphorus are essential nutrients involved in many biological processes. These minerals are the most abundant elements in the body, with 99% of Ca and 80% of P stored in the skeleton as hydroxyapatite, and both play an important role in bone development and mineralization [1]. The remaining Ca is located in the extracellular fluid, plasma, and within cells, and plays pivotal roles in metabolism, blood clotting, enzyme activation, neuromuscular function, muscle contraction, cell adhesion, and intracellular signaling [1]. Nucleic acids, nucleotides, phospholipids, and phosphorylated proteins play a fundamental role in growth, cellular and membrane function, energy metabolism, and acid-base balance, and are the main location of the 20% of P not located in the skeleton [1-3]. SUMMARYIn this paper, we present a review of the current knowledge of calcium and phosphorus metabolism as it relates to homeostatic mechanisms in poultry; contrasts with mammalian systems, as well as information that is available for mammalian systems but not for avian systems, are included. The importance of understanding these homeostatic mechanisms and their effect on Ca and P absorption are discussed briefly in the context of correctly formulating poultry diets. Clearly deficiencies, excesses, or imbalances in Ca and P result in a cascade of changes, including increases or decreases in the absorption of these 2 minerals from the intestinal lumen. The effect of these changes on the actual digestibility of Ca and P from ingredients or diets has not been determined yet; most of the methodologies we used for the determination of P digestibility are done under deficient conditions. The methods used to determine the release of Ca and P from diets when phytases were used were also done under deficient Ca and P conditions. given the effect of Ca and P homeostatic mechanisms on absorption, methodologies and, possibly, the quantitative the effect of these homeostatic mechanisms on values generated for Ca and P should be reviewed before they can confidently be applied.

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Section: Calcium Homeostasissupporting

confidence: 80%

Section: Calcium Homeostasismentioning

confidence: 98%