Abstract:Tepary bean (Phaseolus acutifolius) lectins exhibit differential in vitro cytotoxicity and in vivo antitumorigenic effects against colon cancer by oral administration, but their gastrointestinal interactions and digestion have not yet been assessed. This work evaluated the changes of a recombinant Tepary bean lectin (rTBL‐1) through an in vitro/ex vivo gastrointestinal assay. We developed a polyclonal antibody to selectively detect rTBL‐1 by western blot and immunohistochemical analysis. Protein bioaccessibili… Show more
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