Intestinal microflora promotes Th2-mediated immunity through NLRP3 in damp and heat environments
Yi Luo,
Xinhua Huang,
Haiying Hu
et al.
Abstract:BackgroundWith the worsening of the greenhouse effect, the correlation between the damp-heat environment (DH) and the incidence of various diseases has gained increasing attention. Previous studies have demonstrated that DH can lead to intestinal disorders, enteritis, and an up-regulation of NOD-like receptor protein 3 (NLRP3). However, the mechanism of NLRP3 in this process remains unclear.MethodsWe established a DH animal model to observe the impact of a high temperature and humidity environment on the mice.… Show more
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