Intestinal microflora of newborns with purulent-septic diseases

Volkova, Yu.V.; Romanova, Nadya; Chvanova, N. P.

doi:10.17816/kazmj62318

Cited by 3 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…One approach is the intervention with either prebiotics, probiotics, or other commensal microbes that could be useful in restoring a protective microbiota composition and could thus serve as preventive medical therapy. Oral administration of probiotics together with beneficial prebiotics (i.e., in the form of synbiotics) could moderate the course of some dermatoses [123][124][125].…”

Section: Microbiota As a Therapeutic Tool In The Treatment Of Psoriasismentioning

confidence: 99%

Paradoxical Reactions to Anti-TNFα and Anti-IL-17 Treatment in Psoriasis Patients: Are Skin and/or Gut Microbiota Involved?

Zákostelská

Reiss

Tlaskalová‐Hogenová

et al. 2023

Dermatol Ther (Heidelb)

View full text Add to dashboard Cite

Psoriasis is a chronic, immune-mediated, inflammatory disease primarily affecting the skin. It is currently coming to light that patients with psoriasis have disrupted intestinal barrier and often suffer from comorbidities associated with the gastrointestinal tract. Moreover, there is growing evidence of both cutaneous and intestinal paradoxical reactions during biologic treatment in patients with psoriasis. This review focuses on barrier defects and changes in immune responses in patients with psoriasis, which play an important role in the development of the disease but are also influenced by modern biological treatments targeting IL-17 and TNFα cytokines. Here, we highlight the relationship between the gut–skin axis, microbiota, psoriasis treatment, and the incidence of paradoxical reactions, such as inflammatory bowel disease in patients with psoriasis. A better understanding of the interconnection of these mechanisms could lead to a more personalized therapy and lower the incidence of treatment side effects, thereby improving the quality of life of the affected patients.

show abstract

Section: Microbiota As a Therapeutic Tool In The Treatment Of Psoriasismentioning

confidence: 99%

Paradoxical Reactions to Anti-TNFα and Anti-IL-17 Treatment in Psoriasis Patients: Are Skin and/or Gut Microbiota Involved?

Zákostelská

Reiss

Tlaskalová‐Hogenová

et al. 2023

Dermatol Ther (Heidelb)

View full text Add to dashboard Cite

show abstract

“…7 Penelitian Volvoka, et al, juga menunjukkan bahwa 54% pasien akne vulgaris mengalami perubahan mikroflora usus yang signifikan, hal ini dapat menjelaskan mengapa penambahan probiotik dapat berperan dalam terapi akne vulgaris. 20 Beberapa penelitian di atas mendukung teori Bowe dan Logan 7 bahwa terdapat hubungan antara usus dan kulit, kesehatan organ pencernaan berpengaruh terhadap peradangan sistemik, seperti jerawat. 21 Berdasarkan derajat keparahannya, penelitian ini menunjukkan tidak terdapat hubungan bermakna antara konstipasi dan akne vulgaris derajat ringan, namun terdapat hubungan bermakna antara konstipasi dan akne vulgaris derajat sedang-berat.…”

Section: Hasil Penelitianunclassified

Hubungan antara Konstipasi dengan Akne Vulgaris dan Derajat Keparahannya pada Mahasiswa Kedokteran di Jakarta

Renate

Tanjung

2021

Cermin Dunia Kedokteran

View full text Add to dashboard Cite

Latar Belakang: Teori koneksi organ otak-usus-kulit menunjukkan hubungan erat antara kondisi usus dan kondisi dermatologis. Keadaan konstipasi dapat menyebabkan produk sekretori usus menuju peredaran sistemik yang dapat meningkatkan inflamasi organ kulit, sehingga rentan terhadap akne vulgaris. Metode: Penelitian cross-sectional pada 100 mahasiswa laki-laki usia 17-22 tahun dengan metode stratified random sampling. Penilaian konstipasi menggunakan kuesioner gejala konstipasi berdasarkan Kriteria Rome III dan penilaian derajat keparahan akne vulgaris menggunakan Evaluator Global Severity Score (EGSS). Hubungan antara variabel independen dan dependen diuji menggunakan Chi-Square dan Fisher-exact. Hasil: Didapatkan 100 responden, usia terbanyak yang mengalami akne vulgaris adalah 19 tahun dan usia terbanyak yang mengalami konstipasi adalah 20 tahun.Terdapat hubungan bermakna antara konstipasi dan akne vulgaris (p=0,012). Berdasarkan derajat keparahannya, tidak terdapat hubungan antara konstipasi dan akne vulgaris derajat ringan (p=0,973) namun terdapat hubungan antara konstipasi dan akne vulgaris derajat sedang – berat (p=0,048). Simpulan: Penelitian ini menunjukkan hubungan bermakna antara konstipasi dan akne vulgaris. Background: The theory of brain-intestinal-skin connections shows a relationship between intestinal and dermatological conditions. Constipation stimulate the intestine secretory products towards systemic circulation and increase inflammation of the skin, acne vulgaris. Method: This cross-sectional study involved 100 male students aged 17-22 years with stratified random sampling method. Constipation assessment used constipation questionnaire based on Rome III Criteria and assessment for severity of acne vulgaris used Evaluator Global Severity Score (EGSS). The relationship between independent and dependent variables was tested using Chi-Square and Fisher-exact. Result: Majority respondents who have acne vulgaris is 19 year-old and constipation is mostly found in 20 year-old. There is significant relationship between constipation and acne vulgaris (p=0.012). No significant relationship between constipation and mild acne vulgaris (p=0.973) but there is a significant relationship between constipation and moderate to severe acne vulgaris (p=0.048). Conclusion: This study shows possible role of digestive organ health in acne vulgaris incidence.

show abstract

“…reported a reduction in bacillus abundance in individuals with acne, 13 whereas Volkova et al. observed an increase in its abundance 14 . Many studies investigating the relationship between gut microbiota and acne have utilized a case‐control study design, which makes it challenging to establish a clear causal relationship between the two.…”

Section: Introductionmentioning

confidence: 99%

“…observed an increase in its abundance. 14 Many studies investigating the relationship between gut microbiota and acne have utilized a case‐control study design, which makes it challenging to establish a clear causal relationship between the two. Observational studies are prone to the influence of various confounding factors, including but not limited to environmental factors, age, dietary habits, and lifestyle, which may have an impact on the results.…”

Section: Introductionmentioning

confidence: 99%

Gut microbiota and acne: A Mendelian randomization study

Cao,

Guo,

Chang

et al. 2023

Skin Research and Technology

View full text Add to dashboard Cite

BackgroundPrior observational studies have identified a relationship between the composition of gut microbiota and the onset of acne. To ascertain the causal relationship underlying this association, we adopted the Mendelian randomization (MR) method, which offers a powerful approach to causal inference.MethodsSummary statistics on gut microbiota and acne were obtained from the MiBioGen and FinnGen consortium, respectively. The causal relationship was assessed using multiple methods in a two‐sample framework, including MR Egger, weighted median, inverse variance weighted (IVW), and weighted mode. Furthermore, the heterogeneity and horizontal pleiotropy analyses were conducted, along with the leave‐one‐out method.ResultsThe IVW estimation indicated that Allisonella (odds ratio [OR] = 1.42, 95% confidence interval [CI] = 1.18–1.70, p = 0.0002) and Bacteroides (OR = 2.25, 95% CI = 1.48–3.42, p = 0.0001) have adverse effects on acne. By contrast, Ruminococcus torques group (OR = 0.41, 95% CI = 0.25–0.65, p = 0.0002) showed a beneficial effect on acne. In addition, Candidatus soleaferrea (OR = 0.75, 95% CI = 0.60–0.95, p = 0.0149), Eubacterium coprostanoligenes group (OR = 0.67, 95% CI = 0.47–0.95, p = 0.0230), Fusicatenibacter (OR = 0.71, 95% CI = 0.52–0.97, p = 0.02897), and Lactobacillus (OR = 0.72, 95% CI = 0.58–0.90, p = 0.0046) showed suggestive associations with acne.ConclusionThe present investigation suggests a causal effect of gut microbiota on acne.

show abstract

Intestinal microflora of newborns with purulent-septic diseases

Cited by 3 publications

References 0 publications

Paradoxical Reactions to Anti-TNFα and Anti-IL-17 Treatment in Psoriasis Patients: Are Skin and/or Gut Microbiota Involved?

Paradoxical Reactions to Anti-TNFα and Anti-IL-17 Treatment in Psoriasis Patients: Are Skin and/or Gut Microbiota Involved?

Hubungan antara Konstipasi dengan Akne Vulgaris dan Derajat Keparahannya pada Mahasiswa Kedokteran di Jakarta

Gut microbiota and acne: A Mendelian randomization study

Contact Info

Product

Resources

About