Oral Drug Delivery for Modified Release Formulations 2022
DOI: 10.1002/9781119772729.ch3
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Intestinal Epithelium and Drug Transporters

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Cited by 2 publications
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“…Several uptake (solute carrier transporters; SLCs) and ATP-binding cassette (ABC) efflux transporters are located in the apical membrane of enterocytes. SLCs facilitate drug absorption and are the most abundant transporters in the small intestine [9], while ABC transporters limit intestinal absorption and promote the excretion of endogenous substances [10]. In addition, NRs function as modulators of drug-metabolizing enzymes and DT expression [11].…”
Section: Introductionmentioning
confidence: 99%
“…Several uptake (solute carrier transporters; SLCs) and ATP-binding cassette (ABC) efflux transporters are located in the apical membrane of enterocytes. SLCs facilitate drug absorption and are the most abundant transporters in the small intestine [9], while ABC transporters limit intestinal absorption and promote the excretion of endogenous substances [10]. In addition, NRs function as modulators of drug-metabolizing enzymes and DT expression [11].…”
Section: Introductionmentioning
confidence: 99%