“…In adults, the use of a loss of resistance to air technique has also been implicated in producing areas of incomplete analgesia [78,79], subcutaneous emphysema [80], lumbar nerve root compression with symptoms [81,82] and interscapular pain [83]. Because of these considerations, most workers now recommend that a loss of resistance to saline technique is used in preference to a loss of resistance to air technique [84], despite the fact that the loss of resistance to air ............................................................................................................................................................................................................................................. technique is considered by many to give a superior feel when performing epidural cannulation, has been found to result in fewer dural punctures than a loss of resistance to saline technique and in the event of any leakage of fluid there is no confusion about whether or not a dural tap has occurred [61]. The use of carbon dioxide in the loss of resistance syringe to provide the benefits of air without its risks has been suggested [61].…”