Interventions Using Electronic Medical Records Improve Follow Up of Infants Born to Hepatitis C Virus Infected Mothers

Abughali, Nazha; Maxwell, Jessie R.; Kamath, Aparna; Nwankwo, Uchebike; Mhanna, Maroun J.

doi:10.1097/inf.0000000000000129

Cited by 10 publications

(7 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Finally, only 62% of HCV positive participants responded that infants born to HCV positive mothers must be tested by a pediatrician. These results are consistent with reports that HCV testing rates for perinatally exposed children are alarmingly inadequate (Abughali, Maxwell et al 2014). In an evaluation of pediatric testing rates for children born to over 500 HCV positive women in the Philadelphia Hepatitis Registry, only 16% of HCV-exposed children were tested for HCV (Kuncio, Newbern et al 2016).…”

Section: Discussionsupporting

confidence: 92%

Hepatitis C Virus Knowledge Among Pregnant Women with Opioid Use Disorder

Rothenberger

Morrison

Park

et al. 2018

Matern Child Health J

View full text Add to dashboard Cite

Objectives To evaluate Hepatitis C virus (HCV) knowledge and awareness among pregnant women with opioid use disorder (OUD). Methods From May through November 2015, a one-time survey was distributed to a convenience sample of pregnant women with OUD to assess their knowledge and awareness of (a) risk factors for HCV infection, (b) HCV transmission prevention strategies, (c) hepatotoxic risk reduction and (d) perinatal transmission and neonatal implications of HCV infection. Chi square and Fisher's exact tests were used to compare demographic characteristics and HCV knowledge between participants who were HCV positive and negative. Results Of 179 pregnant women with OUD approached, 169 (94%) completed the survey. Of these, 153 (90.5%) reported at least one risk factor for HCV infection, 85 (50.3%) were HCV positive and 38 (44.7%) of HCV positive women were diagnosed with HCV for the first time during pregnancy. When HCV knowledge was evaluated, 114 (66.7%) responded that sharing eating utensils could transmit HCV, 69 (55.0%) responded that there is a vaccine to prevent HCV and 56 (32.7%) did not identify intranasal drug use as a risk factor for HCV transmission. Among HCV positive women, 61 (71.8%) associated breastfeeding with an increased risk for HCV transmission, 33 (38.1%) failed to identify the importance of pediatric follow-up for HCV-exposed children and 16 (18.8%) perceived the risk of HCV vertical transmission as "likely" or "very likely." Conclusions for Practice Gaps in HCV knowledge exist among a rapidly growing population of pregnant women with OUD. Healthcare providers have a unique opportunity to provide HCV education and counseling during pregnancy.

show abstract

Section: Discussionsupporting

confidence: 92%

Hepatitis C Virus Knowledge Among Pregnant Women with Opioid Use Disorder

Rothenberger

Morrison

Park

et al. 2018

Matern Child Health J

View full text Add to dashboard Cite

show abstract

“…It is associated with improvements in maternal and neonatal care, and may make record linkage seamless in the future. 23 24 During the response to a novel threat, adapting existing information collection systems, such as the Zika Pregnancy and Infant Registry c and Zika Birth Defects Surveillance system d public health databases to facilitate record linkage may reduce time to implementation.…”

Section: Discussionmentioning

confidence: 99%

“…It is associated with improvements in maternal and neonatal care, and may make record linkage seamless in the future. 23,24 During the response to a novel threat, adapting existing information collection systems, such as the Zika Pregnancy and Infant Registry c and Zika Birth Defects Surveillance system d public health databases to facilitate record linkage may reduce time to implementation. However, available medical and public health databases have limited utility for health care provider tracking of individual mother-infant pairs, can be geographically exclusive, and incompatible with systems outside a particular catchment area, and may have limited accessibility.…”

Section: Children's Interdisciplinary Care Coordination Frameworkmentioning

confidence: 99%

“…The ChICC framework may promote a better understanding and reinforcement of communication strategies among pre-, peri-, and postnatal health care professionals to provide optimal care in both routine and emergency response settings, as well as inform and improve preparedness efforts, for novel and emerging congenital infections. In combination with lessons learned from existing models for transferring critical information between obstetric and pediatric health care teams, 23,[28][29][30][31] the ChICC framework may facilitate clinicians' ability to leverage methods used for addressing other congenital infections.…”

Section: Implications and Remaining Gapsmentioning

confidence: 99%

See 1 more Smart Citation

A Framework for Coordination between Obstetric and Pediatric Providers in Public Health Emergencies: Lessons Learned from the Zika Outbreak in the United States, 2015 to 2017

et al. 2020

View full text Add to dashboard Cite

Emergency response to emerging threats with the potential for vertical transmission, such as the 2015 to 2017 response to Zika virus, presents unique clinical challenges that underscore the need for better communication and care coordination between obstetric and pediatric providers to promote optimal health for women and infants. Published guidelines for routine maternal-infant care during the perinatal period, and models for transitions of care in various health care settings are available, but no broad framework has addressed coordinated multidisciplinary care of the maternal-infant dyad during emergency response. We present a novel framework and strategies to improve care coordination and communication during an emergency response. The proposed framework includes (1) identification and collection of critical information to inform care, (2) key health care touchpoints for the maternal-infant dyad, and (3) primary pathways of communication and modes of transfer across touchpoints, as well as practical strategies. This framework and associated strategies can be modified to address the care coordination needs of pregnant women and their infants with possible exposure to other emerging infectious and noninfectious congenital threats that may require long-term, multidisciplinary management. Key Points

show abstract

“…Improved identification of vertically-infected children will require both better detection of HCV-infected pregnant women [39], possibly through implementation of universal antenatal screening in some locales [40], and more comprehensive efforts to ensure that vertically-exposed infants receive proper testing. Strategic use of electronic medical record systems to track HCV-exposed infants and inclusion of early HCV-RNA PCR (such as at age 2 months) in the testing schema may be means to reduce the number of children who are lost to follow-up without any HCV testing [41]. Increased screening of adolescents with a history of IDU is also needed to ensure that more horizontally-acquired cases are identified.…”

Section: Prospects For Bringing Daas To Childrenmentioning

confidence: 99%

New prospects for the treatment and prevention of hepatitis C in children

Ohmer¹,

Honegger

2016

Current Opinion in Pediatrics

View full text Add to dashboard Cite

Purpose of review Combined pegylated interferon-α and ribavirin remain the standard therapy for pediatric hepatitis C virus (HCV) infection in 2016, but direct acting antivirals (DAAs) with greatly improved efficacy and safety are now approved for adults. Here we review the major classes of DAAs and their anticipated use for treatment and potentially prevention of HCV in children. Recent findings Currently approved DAAs target the viral protease, polymerase, and NS5A, a protein involved in viral replication and assembly. In combination, they have lifted sustained virologic response rates to over 90% for multiple HCV genotypes, and the rich DAA pipeline promises further improvements. Clinical trials of interferon-free DAA regimens have been initiated for children ages 3–17 years. The first efficacy trial of a preventative HCV vaccine for adults is also underway. While awaiting a vaccine, there is hope that increased DAA uptake may prevent pediatric HCV infections by shrinking the pool of infectious persons. Summary Interferon-free DAA regimens have revolutionized therapy for HCV-infected adults and pending results of pediatric trials will likely do the same for HCV-infected children. If widely deployed, particularly amongst individuals likely to transmit HCV, DAA therapies may also help reduce new vertically- and horizontally-acquired pediatric infections.

show abstract

Interventions Using Electronic Medical Records Improve Follow Up of Infants Born to Hepatitis C Virus Infected Mothers

Abstract: Interventions using EMR improved the identification and appropriate HCV follow up of infants born to HCV-infected mothers.

Cited by 10 publications

References 16 publications

Hepatitis C Virus Knowledge Among Pregnant Women with Opioid Use Disorder

Hepatitis C Virus Knowledge Among Pregnant Women with Opioid Use Disorder

A Framework for Coordination between Obstetric and Pediatric Providers in Public Health Emergencies: Lessons Learned from the Zika Outbreak in the United States, 2015 to 2017

New prospects for the treatment and prevention of hepatitis C in children

Contact Info

Product

Resources

About