Interventions to Improve Medication Adherence in Schizophrenia

Zygmunt, Annette; Olfson, Mark; Boyer, Carol A.; Mechanic, David

doi:10.1176/appi.ajp.159.10.1653

Cited by 447 publications

(360 citation statements)

References 68 publications

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“…Currently there are no evidence-based interventions specifically to improve psychotropic medication adherence among Latinos. However, findings from broader quality improvement interventions (74), adherence interventions in predominantly non-Latino populations (75, 76), adherence interventions for non-psychiatric diseases tested in Latinos (77–79), broader mental health interventions for Latinos (80, 81), from clinical experience (82) and policy papers (39) are potentially applicable.…”

Section: Discussionmentioning

confidence: 99%

Psychotropic Medication Nonadherence Among United States Latinos: A Comprehensive Literature Review

Lanouette¹,

Folsom²,

Sciolla³

et al. 2009

Psychiatric Services

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Objective Psychotropic medication nonadherence is a major public health problem, but few studies have focused on Latinos. We systematically reviewed the literature on rates of and factors influencing antipsychotic, antidepressant, or mood stabilizer nonadherence among United States (US) Latinos. Methods Data Sources: MEDLINE and PsycINFO were searched using keywords adherence, compliance, Latino, Hispanic, psychotropic, and related terms, as well as bibliographies from relevant reviews and studies. Study Selection: 21 studies met inclusion criteria: published since 1980 in English or Spanish; measured psychotropic medication nonadherence rates among US Latino adults. Data Abstraction: We examined articles for study design and objective, location, population, medication type, participant demographics, adherence measure, adherence rates, and factors related to adherence. Results and Conclusions In studies including Latinos and other ethnic groups, mean nonadherence rates were 41%, 31%, and 43% among Latinos, Euro-Americans, and African Americans respectively, with an overall effect size of 0.64 between Latinos and Euro-Americans. In studies including only Latinos, the mean nonadherence rate was 44%. Ten of 16 studies found Latinos had significantly lower adherence rates than Euro-Americans. Risk factors for nonadherence included being monolingual Spanish speaking, lacking health insurance, experiencing barriers to quality care, and having lower socioeconomic status. Protective factors included family support and psychotherapy. Rates of nonadherence to psychotropic medications were higher for Latinos than for Euro-Americans. Further investigation is needed into the potentially modifiable individual and societal level mechanisms of this discrepancy. Clinical and research interventions to improve adherence should be culturally appropriate and incorporate identified factors.

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Section: Discussionmentioning

confidence: 99%

Psychotropic Medication Nonadherence Among United States Latinos: A Comprehensive Literature Review

Lanouette¹,

Folsom²,

Sciolla³

et al. 2009

Psychiatric Services

View full text Add to dashboard Cite

show abstract

“…Psikiyatrik bozukluğu olan hastalar tipik olarak tedavi rejimini takip etmede büyük güçlük yaşarlar, ayrıca tedaviye uyum sağlandığın-da da tedaviden yarar görme olasılıkları da büyük oranda artar (7,8). Fiziksel hastalığı olan hastalarda tedaviye…”

Section: Hasta Uyumu Ve Etkililikunclassified

Tedavide Hızlı Salınımlı ve Uzatılmış Salınımlı Formülasyonların Farkları

Üresin

Baran

2011

Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychophar

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“…Although an extensive body of literature suggests that inperson, problem-solving interventions can improve psychiatric medication adherence for persons with SSDs, such interventions are expensive and poorly suited for community implementation [9][10][11]. Where they even exist, problemsolving programs are offered to only the most severely ill persons due to cost and personnel constraints.…”

Section: Introductionmentioning

confidence: 99%