Interventions for treating simple bone cysts in the long bones of children

BMC Musculoskelet Disord

Zhao

et al. 2021

Background The unicameral bone cyst (UBC) is a kind of benign tumor whose clinical treatments and efficacy are controversial. The purpose of this study was to evaluate the efficacy of the elastic stable intramedullary nail (ESIN), the injection of autologous bone marrow (ABM), and the combination of ESIN and ABM in the treatment of bone cyst in children. Methods Eighty-three cases with simple bone cyst were analyzed retrospectively. Twenty-eight cases were treated with ABM. Twenty-eight cases were treated with ESIN. Twenty-seven cases were treated with ABM and ESIN. All cases were diagnosed through X-ray, CT, or MRI scans. For the suspicious ones, the pathological biopsy was performed for an accurate diagnosis. X-ray examinations were carried out for the postoperative follow-up. Capanna criteria for bone cyst was used for postoperative evaluation of three methods. Results All cases accomplished the follow-up. The effective rate of the ABM + ESIN group was significantly higher than that of the ABM group (P < 0.05), and the cure rates of the ESIN group and the ABM + ESIN group were higher than that of the ABM group (P < 0.05, respectively). The cure time in the ESIN group was lower than that of the other two groups (P < 0.05, respectively). The times for admission were 2.0 ± 0.0 in the ESIN group, 5.7 ± 1.9 in the ABM group, and 4.7 ± 2.4 in the ABM + ESIN group (P < 0.05 when compared with each other). Conclusions The method of ABM combined with ESIN for children’s bone cyst has the highest effective rate and curative rate. For the individual method, ESIN has a higher effective rate and curative rate than that of ABM. Meanwhile, it has the fewest time of hospitalization.

Section: Introductionmentioning

confidence: 99%

Comparison of three treatment methods for simple bone cyst in children

BMC Musculoskelet Disord

Zhao

et al. 2021

“…The etiology and pathogenesis of UBC in children have not been identi ed 3 . There are many treatment methods in clinical practice for bone cysts, such as autograft or allograft bone grafting after lesion curettage [3][4][5] , local injection of autogenous bone marrow (ABM) [6][7] or methylprednisolone 8 and implantation of elastic stable intramedullary nail (ESIN) [9][10][11] . Among them, local injection of ABM and implantation of ESIN are used widely.…”

Section: Introductionmentioning

confidence: 99%

Comparison of three treatment methods for simple bone cyst in children

Zhao³

et al. 2020

Preprint

Background To evaluate the efficacy of the elastic stable intramedullary nail (ESIN), the injection of autologous bone marrow (ABM) and the combination of ESIN and ABM in the treatment of children simple bone cyst. Methods 83 children with simple bone cyst were analyzed retrospectively. 28 cases were treated with ABM. 28 cases were treated with ESIN. 27 cases were treated with ABM combined with ESIN. All cases were diagnosed through X-ray plains, CT or MRI scans. For the suspicious ones, pathological biopsy was performed for an accurate diagnosis. X-ray examination were carried out for the postoperative follow-up. Capanna criteria for bone cyst was used for the postoperative evaluation of the three methods. Results All the cases accomplished the follow-up. The effective rate of ABM + ESIN group was significantly higher than that of the ABM group (P < 0.05), and the cure rates of ESIN group and ABM + ESIN group were higher than that of ABM group (P < 0.05, respectively). The cure time in ESIN group was lower than that of the other two groups (P < 0.05, respectively). The times for admission were 2.0 ± 0.0 in ESIN group, 5.7 ± 1.9 in ABM group and 4.7 ± 2.4 in ABM + ESIN group (P < 0.05 when compared with each other). Conclusion The method of ABM combined with ESIN for children bone cyst has the highest effective and curative rate.For individual method, ESIN has a higher effective rate and curative rate than that of ABM with the lowest time of admission.

“…The etiology and pathogenesis of UBC in children have not been identi ed 3 . There are many treatment methods in clinical practice for bone cysts, such as autograft or allograft bone grafting after lesion curettage [3][4][5] , local injection of autogenous bone marrow (ABM) [6][7] or methylprednisolone 8 , and implantation of elastic stable intramedullary nail (ESIN) [9][10][11] et al Among them, local injection of ABM and implantation of ESIN are used widely. However, the comparison of clinical e cacy among ABM, ESIN and ABM combined with ESIN is rarely reported.…”

Section: Introductionmentioning

confidence: 99%

Comparison of three treatment methods for simple bone cyst in children

Zhao³

et al. 2020

Preprint

Background Unicameral bone cyst (UBC) is a benign tumor whose clinical treatments and efficacy are controversial. The purpose of this study was to evaluate the efficacy of the elastic stable intramedullary nail (ESIN), the injection of autologous bone marrow (ABM) and the combination of ESIN and ABM in the treatment of simple bone cyst of children.Methods 83 children with simple bone cyst were analyzed retrospectively. 28 cases were treated with ABM. 28 cases were treated with ESIN. 27 cases were treated with ABM and ESIN. All cases were diagnosed through X-ray, CT or MRI scans. For the suspicious ones, pathological biopsy was performed for an accurate diagnosis. X-ray examinations were carried out for the postoperative follow-up. Capanna criteria for bone cyst was used for the postoperative evaluation of the three methods.Results All the cases accomplished the follow-up. The effective rate of ABM+ESIN group was significantly higher than that of the ABM group (P<0.05), and the cure rates of ESIN group and ABM+ESIN group were higher than that of ABM group (P<0.05, respectively). The cure time in ESIN group was lower than that of the other two groups (P<0.05, respectively). The times for admission were 2.0±0.0 in ESIN group, 5.7±1.9 in ABM group and 4.7±2.4 in ABM+ESIN group (P<0.05 when compared with each other).Conclusions The method of ABM combined with ESIN for children bone cyst has the highest effective and curative rates. For individual method, ESIN has a higher effective rate and curative rate than that of ABM with the lowest time of admission.