Pruritus, a ubiquitous symptom with a wide range of presentations, often causes considerable distress for many individuals, resulting in a reduced quality of life. In recent years, there has been renewed interest and increased research activity in this previously neglected field. Although there is still much to be learnt about the mechanisms of pruritus, the clinician's antipruritic armoury is steadily improving. The key to successful management is early recognition together with accurate and holistic patient assessment. This article aims to provide an overview of the management and treatment of pruritus. The words ‘pruritus’ and ‘itch’ are used interchangeably in this article.