Interventions for the prevention of recurrent erysipelas and cellulitis

Abstract

Cochrane Database of Systematic Reviews penicillin and one erythromycin), which was compared to either no treatment or placebo, and one trial used selenium compared to physiological salt solution. Treatments lasted from six to 18 months.The most common setting was the hospital, and two studies were multicentre. The studies were conducted in the UK, Sweden, Tunisia, Israel, and Austria. There was a small number of previous episodes of cellulitis in those recruited to the trials, ranging between one and four episodes in each study. The antibiotic trials assessed prevention with antibiotics in people with cellulitis of the legs, and the selenium trial assessed people with cellulitis of the arms. Key resultsOur main outcome was prevention of repeated episodes of cellulitis. Our other outcomes included the number of repeated attacks of cellulitis, time to next attack, hospitalisation, quality of life, development of antibiotic resistance, adverse reactions and death.Combining the results of all five trials that used antibiotics, we found moderate-certainty evidence that for those people under preventative treatment, antibiotic treatment in general, and penicillin in particular, is probably both e ective and safe for the prevention of repeated episodes of leg cellulitis when compared with no treatment or placebo. Interventions for the prevention of recurrent erysipelas and cellulitis (Review)

Hospital costs for patients with lower extremity cellulitis: a retrospective population-based study

“…[8] Risk factor modification including treatment of lymphedema and tinea pedis is also recommended for reduction of cellulitis recurrence. [22]…”

A case report of an Infant erysipelas on a impetigo

“…Prophylaxie secondaire: traitementd'uneported'entrée persistante (antifongique topique encas d'intertrig omycosique) [2], prise en charge des facteurs favorisants (insuffisance veinolymphatique, obésité, etc.). En cas de récidives multiples, une antibiothérapie au long cours possible [6].…”

Which outcomes are reported in cellulitis trials? Results of a review of outcomes included in cellulitis trials and a patient priority setting survey

“…This review included all RCTs that were included in two Cochrane reviews: ‘interventions for the prevention of recurrent erysipelas and cellulitisʼ, published in June 2017, and the Cochrane update: ‘interventions for the treatment of cellulitis and erysipelas’ (awaiting publication but obtained from personal communication with the authors). Studies that assessed treatment or prevention of cellulitis, erysipelas or skin and soft‐tissue infection were included in this review.…”

“…Despite the impact of the disease, there are few well‐conducted trials looking into the treatment and prevention of cellulitis . It has been reported that clinical assessment of cellulitis many not capture the patient's experience, and may be unreliable in reflecting real effects for patients …”