Interventions for psychotic symptoms concomitant with epilepsy

Farooq, Saeed; Sherin, Akhtar

doi:10.1002/14651858.cd006118

Cited by 7 publications

(6 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, in that case series, it was also reported that recurrence of seizures was minimally reduced or unchanged during olanzapine treatment, while participants in the haloperidol group had increased seizures compared to the baseline. Nevertheless, limited evidence in the form of one RCT and a few descriptive studies have shown improvement of psychotic symptoms of epilepsy with antipsychotics [17]. In the present case it may be argued that the symptom improvement was due to spontaneous remission and, in fact, the use of haloperidol might have delayed the spontaneous remission.…”

Section: Discussionmentioning

confidence: 63%

A Case of Complex Partial Seizures Presenting as Acute and Transient Psychotic Disorder

Sultan

Fallata

2019

Case Reports in Psychiatry

View full text Add to dashboard Cite

Introduction. Complex partial seizures are focal (CPS) (i.e., start in one area of the brain) and associated with impairment in consciousness. Most of them arise in the temporal region and are characterized by aura, impaired consciousness, and automatisms. CPS that arise in temporal region are most often misdiagnosed as primary psychiatric illness. Case Report. A 25-year-old male presented with fluctuations in consciousness, aggressive behaviour, hallucination, and delusions of grandeur lasting a few hours. He was diagnosed with acute and transient psychotic disorder according to ICD10 criteria and was treated with intramuscular haloperidol 10mg BID followed by oral olanzapine 10mg. Computed tomography of brain and electroencephalogram were normal. After 15 days he presented again to the outpatient department with complaints of aggressive behaviour and sensory misinterpretations. Video electroencephalogram was recommended, which was not done due to financial constraints. The diagnosis was reconsidered and he was started on oral carbamazepine due to high clinical suspicion, of complex partial seizures, in spite of lack of EEG evidence. He responded well to antiepileptic and symptom remission has maintained well. Conclusion. Patients presenting with psychosis need careful diagnostic evaluation for other possibilities.

show abstract

Section: Discussionmentioning

confidence: 63%

A Case of Complex Partial Seizures Presenting as Acute and Transient Psychotic Disorder

Sultan

Fallata

2019

Case Reports in Psychiatry

View full text Add to dashboard Cite

show abstract

“…In addition, other clinicians advocate claims that low doses of antipsychotics when coupled with an effective antiseizure medication regimen, will not significantly elevate the risk of inducing a seizure in PIP patients and PWE [11]. In terms of antipsychotic efficacy, there is currently insufficient data on the relative efficacy of any one drug over another to inform practice; a literature review of drug randomized controlled trials (RCTs) showed only one study comparing the superior efficacy of olanzapine over haloperidol in the treatment of a small population of patients with POE [13]. Electroconvulsive therapy and repetitive transcranial magnetic stimulation have also been postulated to aid in PIP treatment [11].…”

Section: Discussionmentioning

confidence: 99%

"You Are The One Who Was Beating Me": A Case Report of a Patient with Postictal Psychosis Secondary to Bilateral Temporal Lobe Epilepsy

Ngo¹,

Camacho

Singh

2019

Cureus

View full text Add to dashboard Cite

Postictal psychosis is a rare but potentially serious complication in patients with seizure disorders. There is no consensus on best practices in managing and treating postictal psychosis as well as other psychoses of epilepsy, but current research is investigating topics such as adherence to seizure medications and antipsychotic administration during or before psychosis and addressing psychosocial stressors as potential components of effective treatment. We present a case report detailing a patient's lengthy history of postictal psychosis due to her underlying temporal lobe epilepsy; her disease course as correlated by a diagnostic electroencephalogram (EEG), her history of medication nonadherence, and the treatment of postictal psychosis are also discussed.

show abstract

“…In summary, significant functional improvement was achieved for severe psychotic symptomatology (delusions, social withdrawal and hallucinations) in our patient experiencing partial complex epilepsy using therapeutic methods that have proven to be effective in treating schizophrenic patients. To the best of our knowledge, this is the first case of a psychotherapeutic treatment used effectively in treating refractory epilepsy of this type [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

A patient with medication-resistant epilepsy featuring psychosensorial and psychotic symptoms presenting with significant functional improvement on psychotherapeutic treatment: a case report

et al. 2013

View full text Add to dashboard Cite

BackgroundPartial complex epilepsy with psychosensorial and psychotic symptoms remains a relatively rare condition that can sometimes be mistaken for an axis I psychiatric disorder. There is no specific treatment for this particular type of epilepsy, anti-epileptic medication being the cornerstone of therapeutic intervention with the occasional addition of neuroleptics. Lack of response to anti-epileptic agents is often a sign of poor prognosis and requires risky and sometimes invasive interventions with high morbidity for patients.Case presentationWe report the case of a 21-year-old right-handed Caucasian man of French-Canadian descent who was living with his mother immediately before being hospitalized in a psychiatric setting for the first time. He seemed obsessed with developing new concepts to reach a more ‘perfect’ existence. He also claimed feeling odd sensations in his mind and in his body that could be linked to some sort of ‘evolutionary’ process resulting from spiritual uplift. He reported non-specific visual hallucinations and what sounded like auditory hallucinations and telepathic powers. The first diagnosis was a possible schizophreniform disorder and our patient was hospitalized. Shortly afterwards, an electroencephalogram showed an important subcortical epileptic activity, compatible with partial complex epilepsy with psychosensorial and psychotic symptoms. Despite a negative response to medication, symptoms proper to this type of epilepsy were substantially alleviated using a psychotherapeutical treatment intended for patients with psychotic disorders, namely integrated psychological therapy (IPT). Significant functional improvement in our patient has been achieved since then.ConclusionsThis case report illustrates that despite a negative response to medication, symptoms proper to this type of epilepsy could be substantially alleviated using psychotherapeutical treatment modalities. To the best of our knowledge, this is the first time such a finding has been reported in the scientific literature. This could open the way for new research themes and therapeutic interventions for such patients.

show abstract

Interventions for psychotic symptoms concomitant with epilepsy

Cited by 7 publications

References 28 publications

A Case of Complex Partial Seizures Presenting as Acute and Transient Psychotic Disorder

A Case of Complex Partial Seizures Presenting as Acute and Transient Psychotic Disorder

"You Are The One Who Was Beating Me": A Case Report of a Patient with Postictal Psychosis Secondary to Bilateral Temporal Lobe Epilepsy

A patient with medication-resistant epilepsy featuring psychosensorial and psychotic symptoms presenting with significant functional improvement on psychotherapeutic treatment: a case report

Contact Info

Product

Resources

About