Interventions for primary vesicoureteric reflux

Abstract

Analysis 2.2. Comparison 2 Surgical reimplantation of ureters plus antibiotics versus antibiotics alone, Outcome 2 Renal parenchymal defects (scars and thinning) on IVP: unit of analysis (children).

Usefulness of intraoperative voiding cystourethrogram as an indicator of sucess in the endoscopic treatment of vesicoureteral reflux

“…However, although polydimethylsiloxane has not been approved in children yet, efficacy in the pediatric population has been widely acknowledged in the literature (15)(16)(17) . In our study, similarly to what Williams G et al reported in their 2019 meta-analysis (18) , healing rates were similar with both materials. Their tendency towards partial reabsorption was described by Kirsch et al's study, where an 18% volume reduction was noted after 2 weeks, with an extra 1% 3 months following surgery (10) .…”

Usefulness of intraoperative voiding cystourethrogram as an indicator of sucess in the endoscopic treatment of vesicoureteral reflux

“…However, although polydimethylsiloxane has not been approved in children yet, efficacy in the pediatric population has been widely acknowledged in the literature (15)(16)(17) . In our study, similarly to what Williams G et al reported in their 2019 meta-analysis (18) , healing rates were similar with both materials. Their tendency towards partial reabsorption was described by Kirsch et al's study, where an 18% volume reduction was noted after 2 weeks, with an extra 1% 3 months following surgery (10) .…”

Current management of symptomatic vesicoureteral reflux in pediatric kidney transplantation—A European survey among surgical transplant professionals

“…This practice is in line with the strategy of the previously surveyed pediatric nephrologists 11 . Furthermore, this approach reflects the current trend to treat primary pediatric VUR, at least in the younger age groups with the likelihood of maturation over time due to the less invasive procedure 5,18 …”

“…When surgical treatment is chosen for symptomatic native kidney VUR, endoscopic subureteric injection is slightly preferred over surgical ureteral reimplantation in the corresponding centers, although the available evidence indicates higher success rates in terms of VUR resolution, lower need for re-intervention, and lower risk of ureteral obstruction in UCN. 5,14,17 This practice is in line with the strategy of the previously surveyed pediatric nephrologists. 11 Furthermore, this approach reflects the current trend to treat primary pediatric VUR, at least in the younger age groups with the likelihood of maturation over time due to the less invasive procedure.…”

Diagnostic and therapeutic management of vesico‐ureteral reflux in pediatric kidney transplantation—Results of an online survey on behalf of the European Society for Paediatric Nephrology

“…Despite the risk of developing resistance to CAP and the uncertain effect of CAP on long‐term kidney outcome, almost two third of the pediatric renal transplant centers use CAP routinely in all renal transplant recipients, partially independent from urological abnormalities and recurrent fUTI 20,36 . Discontinuation of CAP varies considerably with the most often reported criteria removal of the stent, exclusion of VUR by imaging or per transplant protocol in line with other studies 37,38 …”

Usefulness of intraoperative voiding cystourethrogram as an indicator of sucess in the endoscopic treatment of vesicoureteral reflux

“…However, although polydimethylsiloxane has not been approved in children yet, efficacy in the pediatric population has been widely acknowledged in the literature (15)(16)(17) . In our study, similarly to what Williams G et al reported in their 2019 meta-analysis (18) , healing rates were similar with both materials. Their tendency towards partial reabsorption was described by Kirsch et al's study, where an 18% volume reduction was noted after 2 weeks, with an extra 1% 3 months following surgery (10) .…”

Current management of symptomatic vesicoureteral reflux in pediatric kidney transplantation—A European survey among surgical transplant professionals

“…This practice is in line with the strategy of the previously surveyed pediatric nephrologists 11 . Furthermore, this approach reflects the current trend to treat primary pediatric VUR, at least in the younger age groups with the likelihood of maturation over time due to the less invasive procedure 5,18 …”

“…When surgical treatment is chosen for symptomatic native kidney VUR, endoscopic subureteric injection is slightly preferred over surgical ureteral reimplantation in the corresponding centers, although the available evidence indicates higher success rates in terms of VUR resolution, lower need for re-intervention, and lower risk of ureteral obstruction in UCN. 5,14,17 This practice is in line with the strategy of the previously surveyed pediatric nephrologists. 11 Furthermore, this approach reflects the current trend to treat primary pediatric VUR, at least in the younger age groups with the likelihood of maturation over time due to the less invasive procedure.…”

Diagnostic and therapeutic management of vesico‐ureteral reflux in pediatric kidney transplantation—Results of an online survey on behalf of the European Society for Paediatric Nephrology

“…Despite the risk of developing resistance to CAP and the uncertain effect of CAP on long‐term kidney outcome, almost two third of the pediatric renal transplant centers use CAP routinely in all renal transplant recipients, partially independent from urological abnormalities and recurrent fUTI 20,36 . Discontinuation of CAP varies considerably with the most often reported criteria removal of the stent, exclusion of VUR by imaging or per transplant protocol in line with other studies 37,38 …”

Usefulness of intraoperative voiding cystourethrogram as an indicator of sucess in the endoscopic treatment of vesicoureteral reflux

“…However, although polydimethylsiloxane has not been approved in children yet, efficacy in the pediatric population has been widely acknowledged in the literature (15)(16)(17) . In our study, similarly to what Williams G et al reported in their 2019 meta-analysis (18) , healing rates were similar with both materials. Their tendency towards partial reabsorption was described by Kirsch et al's study, where an 18% volume reduction was noted after 2 weeks, with an extra 1% 3 months following surgery (10) .…”

Current management of symptomatic vesicoureteral reflux in pediatric kidney transplantation—A European survey among surgical transplant professionals

“…This practice is in line with the strategy of the previously surveyed pediatric nephrologists 11 . Furthermore, this approach reflects the current trend to treat primary pediatric VUR, at least in the younger age groups with the likelihood of maturation over time due to the less invasive procedure 5,18 …”

“…When surgical treatment is chosen for symptomatic native kidney VUR, endoscopic subureteric injection is slightly preferred over surgical ureteral reimplantation in the corresponding centers, although the available evidence indicates higher success rates in terms of VUR resolution, lower need for re-intervention, and lower risk of ureteral obstruction in UCN. 5,14,17 This practice is in line with the strategy of the previously surveyed pediatric nephrologists. 11 Furthermore, this approach reflects the current trend to treat primary pediatric VUR, at least in the younger age groups with the likelihood of maturation over time due to the less invasive procedure.…”

Diagnostic and therapeutic management of vesico‐ureteral reflux in pediatric kidney transplantation—Results of an online survey on behalf of the European Society for Paediatric Nephrology

“…Despite the risk of developing resistance to CAP and the uncertain effect of CAP on long‐term kidney outcome, almost two third of the pediatric renal transplant centers use CAP routinely in all renal transplant recipients, partially independent from urological abnormalities and recurrent fUTI 20,36 . Discontinuation of CAP varies considerably with the most often reported criteria removal of the stent, exclusion of VUR by imaging or per transplant protocol in line with other studies 37,38 …”