Interventions for orbital lymphangioma

Acute Unilateral Proptosis After Blunt Orbital Trauma in an Adolescent Patient

“…4 Interventions include observation, intralesional sclerosants, systemic medications like sildenafil and sirolimus, and surgery. 5 Sildenafil and sirolimus have been shown to be effective, albeit with possible adverse effects for the latter including nausea, peripheral edema, hypertriglyceridemia, fever, and diarrhea. [6][7][8] Surgery is typically reserved for acute situations when there is potential for irreversible vision loss.…”

Managing Recurrent Orbital Lymphangioma in a Pubertal Female with Negative Pressure Aspiration and Intralesional Bleomycin Injection: A Case Report

“…There are no published randomized control trials on the treatment of orbital lymphangioma. Thus, the effectiveness of medical or surgical treatment on orbital lymphangioma cannot be compared (Patel et al, 2019). Sclerotherapy has been popular in the past three decades in the management of orbital lymphangioma.…”

Unilateral coexisting lymphovenous malformation with persistent fetal vasculature: A case report and short review

“…Orbital lymphatic malformations also known as orbital lymphangiomas, are benign vascular and lymphatic tumours of the head and neck which are usually diagnosed in early childhood. 2,4 They represent 1-3% of the orbital masses. 2 They can present with ptosis, proptosis, restriction of ocular motility, compressive optic neuropathy and disfigurement.…”

“…2 They can present with ptosis, proptosis, restriction of ocular motility, compressive optic neuropathy and disfigurement. 4 The exact etiology of a conjunctival lymphatic malformation is not yet understood. It is usually of sporadic occurrence and can be occasionally associated with the Turner syndrome or the Nonne-Milroy-Meige disease.…”

“…2 There is no gold standard for treatment and regular follow-up with observation has been opted for by clinicians and patients in many instances like our patient and his family. 4 This child had decreased visual acuity due to the coexistence of persistent hyperplastic primary vitreous (PHPV) with the lymphovenous malformation and other associated ocular morbidities like cataract. PHPV is a rare congenital developmental malformation of the eye in which there is a retrolental fibrovascular mass caused by persistence of the primary vitreous that normally regresses during the embryonic development of the eye.…”