Interventions for diabetic macular oedema: a systematic review of the literature

Abstract

Although laser treatment remains the cornerstone of treatment in diabetic macular oedema, the literature is beginning to support combination therapy. Using one or two intravitreal injections to reduce central macular thickness followed by focal or grid laser to give a sustained response may offer an alternative to treatment in DMO.

Meta-analysis and review on the effect of bevacizumab in diabetic macular edema

“…However, the potential destructive effect of laser therapy cannot be overlooked, and there is increasing evidence for benefit with combination therapy in DME. Accordingly, other authors have pointed out the short-term effect of anti-angiogenic agents and have suggested using one or two intravitreal injections of anti-angiogenic agents to reduce central macular thickness, followed by focal or grid laser to give a sustained response as an alternative to treatment in DME [51].…”

Comparison of the Efficacy of Sub-Tenon versus Intravitreal Triamcinolone Acetonide Injection during Cataract Surgery for Diabetic Macular Edema

“…Diabetic macular edema (DME) is the most common causes of unfavorable visual effects in patients with nonproliferative diabetic retinopathy [1]. A past meta-analysis found that 6.81% of 22,896 diabetic patients had DME [2].…”

Efficacité des implants intravitréens de dexaméthasone dans l’œdème maculaire hors occlusions veineuses : résultats sur une cohorte de 80 patients

“…Le deuxième inconvénient est l'induction d'une cataracte [11], dont la fréquence est estimée à 50 % environ [12,13]. Les implants injectables intravitréens présentent l'intérêt d'une libération prolongée et donc d'une moindre fréquence d'injection [14,15].…”