2018
DOI: 10.1007/s00392-018-1290-7
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Interventional treatment of paravalvular regurgitation by plug implantation following prosthetic valve replacement: a single-center experience

Abstract: In this single-center series interventional PVL closure appears promising for patients at high surgical risk with symptomatic paravalvular regurgitation. Gaining experience in interventional PVL closure at specialized sites will further improve safety and efficacy of this relatively new treatment option. All patients should be treated within large clinical registries to gain more data on mid- and long-term efficacy of transcatheter PVL closure.

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Cited by 11 publications
(8 citation statements)
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“…We can close most PVLs (width <10 mm, and length of <15 mm) via the brachial artery approach. Several previous studies have reported that the clinical success rate of transcatheter closure of PVL ranged from 69.5 to 93% (13)(14)(15). In our study, nine patients achieved clinical improvement.…”
Section: Discussionsupporting
confidence: 52%
“…We can close most PVLs (width <10 mm, and length of <15 mm) via the brachial artery approach. Several previous studies have reported that the clinical success rate of transcatheter closure of PVL ranged from 69.5 to 93% (13)(14)(15). In our study, nine patients achieved clinical improvement.…”
Section: Discussionsupporting
confidence: 52%
“…While a number of devices have European approval, there are currently no occluder devices approved by the United States Food and Drug Administration specifically to treat PVR 19 . The majority of data surrounding these self‐expanding occluder devices are from procedures treating a focal jet of PVR and have shown a high degree of success (>85%) and minimal rates (3.8%‐10%) of procedural complications 9,10,13,14,20‐22 . Devices available include the Amplatzer vascular occluders, Amplatzer duct occluders, Amplatzer septal occluders, and Occlutech Paravalvular Leak Devices, with selection of specific device tailored to the patient (Figure 3).…”
Section: Discussionmentioning
confidence: 99%
“…In comparison with CT and cardiac MRI, TEE is invasive and associated with an approximately 0.9% risk of complications such as esophageal perforation, bleeding, sedation-related events, arrhythmia, and even death. 10,11 For patients unable to undergo TEE due to swallowing difficulties or other gastrointestinal problems, cardiac MRI and CT represent viable options for ruling out LAA thrombus prior to ablation. In contrast, TEE is portable and does not use iodinated or gadolinium contrast agents.…”
Section: Preprocedural Imagingmentioning
confidence: 99%