Intervention and Prevention of Dementia in the Greater Bay Area (GBA) of China

Abstract

Reserve and resilience are recognized as essential for effective intervention and prevention of dementia. However, it is not known if these factors also protect against risk for dementia in the Greater Bay Area (GBA) of Mainland China. Studies of risk factors across regions of China provide an evidence base for future research in the GBA. However, population-based studies are rare and do not account for the cultural differences in levels of education, income, literacy and modifiable lifestyle factors. Critically, extant studies do not allow for differences in languages spoken across the region, which will bias results and potentially minimize true prevalence. Based on the conclusions reported in this Special Collection, research in the GBA should focus on resilience and reserve using preserved native language communication skills.

Pathophysiology characterization of Alzheimer’s disease in South China’s aging population: for the Greater-Bay-Area Healthy Aging Brain Study (GHABS)

“…MCI and dementia individuals had higher depression scores than SCD and NC individuals, whereas SCD individuals showed higher depression scores than NC individuals. The demographic data of the GHABS cohort by cities are summarized in Supplemental Tables 2 and have been compared with the corresponding demographcis from the literature, as presented in Supplemental Table 3 [ 48 , 49 ].…”