Interval Appearance of Glioblastomas Not Evident in Previous CT Examinations

Bolender, Nicole; Cromwell, Laurence D.; Graves, V B; Margolis, Mitchell L.; Kerber, Charles W.; Wendling, Lyle R.

doi:10.1097/00004728-198308000-00004

Cited by 21 publications

(8 citation statements)

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“…4,8,9,11,[13][14][15]18,20,22) Similarly, all of our patients developed high grade gliomas. The origin of malignant tumor cells in the brain is unknown, and the initiation of high grade glioma needs further investigation.…”

Section: Discussionsupporting

confidence: 51%

“…Experience of false-negative detection of glioma by CT indicates that important factors include small tumor size and low cell density, isodense tumor mass, absence of acquired changes in the blood-brain barrier, and poor scan resolution. 4,9,14,18,20) We suggest that MR imaging may fail to detect gliomas due to similar factors.…”

Section: Discussionmentioning

confidence: 90%

“…Many patients have developed CT or MR imaging changes within 6 months, 4,8,9,11,15,18,20) and rapid follow-up CT or MR imaging is recommended. 11,12,20) However, the interval of surveillance CT or MR imaging is unclear.…”

Section: Discussionmentioning

confidence: 99%

“…Computed tomography (CT) has failed to detect glioma at initial and later examinations. 4,9,18,20) The introduction of magnetic resonance (MR) imaging has greatly improved the detection of intracranial lesions, 4,8,9,13,22) and apparently solved the difficulty with the diagnosis of glioma. However, neurosurgeons, neurologists, and neuroradiologists still encounter patients with high grade gliomas who present with no or minimal abnormalities on initial MR imaging.…”

Section: Introductionmentioning

confidence: 99%

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Early Appearance of High Grade Glioma on Magnetic Resonance Imaging

Nishi

Kawai

Yonezawa

et al. 2009

Neurol. Med. Chir.(Tokyo)

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The early appearance of high grade glioma on magnetic resonance (MR) imaging was retrospectively reviewed in the clinical records and MR images of 52 patients with intracerebral glioma treated in Osaka General Medical Center between 1997 and 2006. Three patients had no abnormal findings, and four patients had only hyperintense areas on T 2 -weighted imaging at initial MR examination. Five of the seven patients presented with generalized seizures. Six of the seven patients developed tumor progression within only 5 months. All patients underwent surgical tumor resection and the histological diagnoses were all high grade gliomas, glioblastomas in five, gliosarcoma in one, and anaplastic astrocytoma in one. Surveillance MR imaging should be performed at short intervals in adult patients presenting with seizures but with no or minimal abnormalities on initial MR imaging to identify progression of high grade glioma at the earliest opportunity.

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Section: Discussionsupporting

confidence: 51%

Section: Discussionmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Early Appearance of High Grade Glioma on Magnetic Resonance Imaging

Nishi

Kawai

Yonezawa

et al. 2009

Neurol. Med. Chir.(Tokyo)

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“…So, the effects of malignant transformation on the patients of this study could not be assessed. The duration of malignant transformation is variable, ranging from 4 months to more than 3 years [40][41][42]. Some clinical studies reported that patients with LGG will undergo malignant transformation within 5 years in approximately 50% of cases [43,44].…”

Section: Discussionmentioning

confidence: 99%

3′-Deoxy-3′-[18F]fluorothymidine and O-(2-[18F]fluoroethyl)-L-tyrosine PET in Patients with Suspicious Recurrence of Glioma after Multimodal Treatment: Initial Results of a Retrospective Comparative Study

Jeong

Lee

Rhee

et al. 2010

Nucl Med Mol Imaging

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Purpose The purpose of this study was to compare the uptakes and diagnostic accuracies between 3′-deoxy-3′-[ Methods Thirty-two patients who underwent FLT and FET PET due to abnormal enhancement on magnetic resonance (MR) images were included. According to surgical confirmation or follow-up results, patients were divided into those with therapy-related benign changes (TRBCs) and those with recurrence. Recurrences were divided again into initial low-grade glioma (LGG) and high-grade glioma (HGG). The uptakes of FLT and FET were compared with the maximum standardized uptake value (SUVmax) and lesion-to-normal ratio (LNR). The diagnostic accuracies were compared via a receiver-operating-characteristic (ROC) curve analysis. Results The LNRs of FLT in recurrences with initial HGG (8.26±5.02) were significantly higher than those in recurrences with initial LGG (3.43±2.14) and TRBC (1.81± 0.60). The LNRs of FET in recurrence with initial HGG (2.70±0.48) and LGG (3.03±1.32) were significantly higher than those in the TRBC (1.60±0.47). The areas under the ROC curve (AUCs) of FLT and FET for initial LGG were 0.768 and 0.893, respectively. The AUCs of FLT and FET for initial HGG were 1.000 and 0.964. However, there were no statistical significances. The results for comparing with SUVmax were the same as those with LNR. Conclusions Uptakes of FLT were different according to initial grade in patients with recurrent glioma, but those of FET were not. However, there were no statistical significances in the diagnostic accuracies according to initial grade between the two tracers in this study.

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Computed tomography in the diagnosis of intracranial neoplasms in children

Segall

Batnitzky

Zee

et al. 1985

Cancer

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The authors discuss their original observations using computed tomography (CT) in the diagnosis of posterior fossa neoplasms in children. The subject of CT diagnosis of childhood supratentorial tumors is also reviewed. However, despite the documented value of CT, the authors believe that magnetic resonance imaging (MRI) will eventually offer certain advantages that will make MRI the primary imaging modality for intracranial neoplasms in children.

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Interval Appearance of Glioblastomas Not Evident in Previous CT Examinations

Cited by 21 publications

References 0 publications

Early Appearance of High Grade Glioma on Magnetic Resonance Imaging

Early Appearance of High Grade Glioma on Magnetic Resonance Imaging

3′-Deoxy-3′-[18F]fluorothymidine and O-(2-[18F]fluoroethyl)-L-tyrosine PET in Patients with Suspicious Recurrence of Glioma after Multimodal Treatment: Initial Results of a Retrospective Comparative Study

Computed tomography in the diagnosis of intracranial neoplasms in children

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