Intertwined Detection and Recognition Roles of Tetrazine in Synergistic Anion‐π and H‐bond Based Anion Receptor

Abstract

Supporting information for this article is given via a link at the end of the document.

Design and property investigation on a five-interaction-based fluorescent anion receptor clip

“…Note that such doubly-charged complexes could not be observed with the smaller anion receptor 1. 27 We then tried to obtain structural information about the [(2) n -X] À anions. Starting with [(2) 2 -X] À species, their unimolecular dissociation upon collision induced dissociation (CID) is solely characterized by the elimination of the intact receptor 2 (presently illustrated by Fig.…”

“…These results are in line with our previous publications. 23,27 UV-visible spectra measured during the titration of 2 with chloride anion are reported in Fig. 5.…”

“…35,36 Only one aliphatic mono-substituted tetrazine receptor has been recently reported by us. 27 The impact of a double substitution on receptor properties was therefore evaluated based on descriptors such as (a) geometrical parameters (b) NMR shis (c) photophysical properties and (d) association constants determined by NMR experiments.…”

“…25,26 We recently showed that photophysical properties are particularly useful to characterize anion complexes in solution in a new anion receptor (1) combining a tetrazine and an urea subunits linked by a short exible arm. 27 Examination of the receptor 1 shows that an extra position is available at the tetrazine core for installing an additional urea motif (Scheme 1). We hypothesized that a second nucleophilic aromatic substitution (S N Ar) would enable access to a new family of anion receptors.…”

Understanding the Chloride Affinity of Barbiturates for Anion Receptor Design

“…In the quest for more efficient anion receptors, several studies have employed the use of hydrogen bonding donor molecules in conjunction with other functional systems, like polysubstituted benzene rings. For instance, squaramides, [5] urea, [6,7] pyrrole, [8] and other nitrogen heterocycle compounds [9] are among the most common building blocks to construct anion receptors.…”