“… 4 The chILD syndrome requires the presence of three of the following criteria in the absence of known primary disorders: (1) respiratory symptoms (cough, difficult breathing, or exercise intolerance), (2) respiratory signs (tachypnea, retractions, crackles, digital clubbing, failure to thrive, or respiratory failure), (3) hypoxemia, and (4) diffuse chest infiltrates on chest X-ray (CXR) or computed tomography (CT) scan. 2 , 5 There is an increasing number of reports concerning chILD, especially because of advances in genetic testing methods, but many points still remain unclear. Here, we review the following clinical features of chILD: epidemiology, classification, genetic aspects, diagnosis and treatment.…”