Interstitial glucose and subsequent affective and physical feeling states: A pilot study combining continuous glucose monitoring and ecological momentary assessment in adolescents

Zink, Jennifer; Nicolò, Michele; Imm, Kellie; Ebrahimian, Shayan; Yu, Qihan; Lee, Kyuwan; Zapanta, Kaylie; Huh, Jimi; Dunton, Genevieve F.; Goran, Michael I.; Page, Kathleen A.; Dieli‐Conwright, Christina M.; Belcher, Britni R.

doi:10.1016/j.jpsychores.2020.110141

Cited by 12 publications

(4 citation statements)

References 60 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Participant burden of the data collection can also be decreased by using sensor-based assessments, such as continuous glucose monitors in the study of Zink et al [7]. These authors calculated mean interstitial glucose during time windows in which they also assessed affect and fatigue, and showed that individual relative increases in interstitial glucose relate to subsequent higher positive affective and lower fatigue in healthy young participants.…”

Section: Data Collectionmentioning

confidence: 99%

Putting the spotlight on individual-specific psychosomatic processes: An introduction to the special issue on intensive longitudinal research methods in psychosomatic research

Rosmalen

Ceulemans

2021

Journal of Psychosomatic Research

View full text Add to dashboard Cite

Section: Data Collectionmentioning

confidence: 99%

Putting the spotlight on individual-specific psychosomatic processes: An introduction to the special issue on intensive longitudinal research methods in psychosomatic research

Rosmalen

Ceulemans

2021

Journal of Psychosomatic Research

View full text Add to dashboard Cite

“…Data collection for this study was conducted from May to November 2018. The work presented here is a secondary analysis of pilot data with the primary goal of demonstrating the scalability of combining EMA and continuous glucose monitoring [ 24 ]. Enrollment for this pilot study was performed on a rolling basis until the target sample size (N=15) was met.…”

Section: Methodsmentioning

confidence: 99%

Time-Varying Associations Between Device-Based and Ecological Momentary Assessment–Reported Sedentary Behaviors and the Concurrent Affective States Among Adolescents: Proof-of-Concept Study

Zink¹,

Yang²,

McAlister³

et al. 2022

JMIR Form Res

Self Cite

View full text Add to dashboard Cite

Background Previous studies on affective state–sedentary behavior (SB) associations have not accounted for their potentially time-varying nature and have used inconsistent SB measurement modalities. We investigated whether the strength of the associations between affective states and SB varied as a function of the time of day and by SB measurement modality (device-measured SB vs ecological momentary assessment–reported screen-based SB) in youth. Objective This study aimed to establish a proof of concept that SB–affective state associations may not be static during the day. In addition, we aimed to inform the methodology of future work, which may need to model associations as functions of the time of day and carefully consider how SB is operationalized or measured. Methods A total of 15 adolescents (age: mean 13.07, SD 1.03 years; 10/15, 67% female; 6/15, 40% Hispanic; 10/15, 67% healthy weight) wore thigh-mounted activPAL accelerometers and simultaneously reported their screen-based SBs and concurrent positive and negative affective states via ecological momentary assessment for 7 to 14 days (N=636 occasions). Time-varying effect models (varying slopes) examined how each measure of SB was associated with concurrent affective states from 7 AM to 8 PM. Results Time-varying effect model plots revealed that these associations varied in strength throughout the day. Specifically, device-based SB was related to greater concurrent negative affect only after approximately 5 PM and was unrelated to concurrent positive affect. Screen-based SB was related to greater concurrent negative affect only from 7 AM to approximately 9 AM. This was also related to greater concurrent positive affect from 7 AM to approximately 9:30 AM and from approximately 3 PM to approximately 7 PM. Conclusions We provide preliminary evidence to suggest that future confirmatory studies investigating the SB–affective state relationship should consider the time-varying nature of these associations and SB measurement modality. There may be critical time windows when specific types of SBs co-occur with affect, suggesting that interventions may need tailoring to the time of day and type of SB if future studies using similar methodologies can replicate our findings.

show abstract

“…In real-world settings, eating behavior, and thus glucose variability, is influenced by several individual-level factors. One example of an individual factor that influences eating behavior is affect [ 18 - 21 ]. The relationship between eating behavior and affect appears to be bidirectional as fatigue, stress, and negative mood are associated with increased cravings and food consumption [ 19 - 22 ], while variations in glucose in response to eating may relate to affective and physical feeling states [ 23 - 26 ].…”

Section: Introductionmentioning

confidence: 99%

“…A recent review [ 29 ] of mood and glucose variability in type 1 and 2 diabetes identified only 1 study that used CGMs and EMA to evaluate mood and glucose [ 25 ] and called for more research evaluating the relationships between mood or affect and glucose variability. To date, only a small (n=15) pilot study has combined EMA responses with CGM data to evaluate its association with affective and physical feeling states in nondiabetic samples [ 18 ]. Thus, the aims of this study are to (1) evaluate the feasibility of conducting a study using CGMs and EMA and (2) examine the bidirectional relationship between affect and glucose in adults using CGM and EMA data.…”

Section: Introductionmentioning

confidence: 99%

Real-time Assessment of the Bidirectional Relationship Between Affective States and Glucose: Protocol for a 14-Day Observational Study

Rethorst¹,

Githinji²,

Seguin‐Fowler³

et al. 2023

JMIR Res Protoc

View full text Add to dashboard Cite

Background Glucose variability increases cardiometabolic disease risk. While many factors can influence glucose levels, postprandial glucose response is the primary driver of glucose variability. Furthermore, affect may directly and indirectly impact glucose variability through its effect on eating behavior. Continuous glucose monitors (CGMs) facilitate the real-time evaluation of blood glucose, and ecological momentary assessment (EMA) can be used to assess affect in real time. Together, data collected from these sources provide the opportunity to further understand the role of affect in glucose levels. Objective This paper presents the protocol for a study that aims to (1) evaluate the feasibility and acceptability of using CGMs along with EMA in nondiabetic populations and (2) examine the bidirectional relationship between affect and glucose in nondiabetic adults with overweight or obesity using a CGM and EMA. Methods Eligibility criteria for the study include participants (1) aged 18 to 65 years old, (2) with a BMI of ≥25 kg/m2, (3) who are able to read and write in English, and (4) who own a smartphone. Individuals will be excluded if they (1) have type 1 or 2 diabetes or have any other condition that requires glucose monitoring, (2) are pregnant, (3) use any medications that have the potential to alter blood glucose levels or interfere with the glucose sensing process, or (4) have a diagnosed gastrointestinal condition or eating disorder. In a 14-day observational study, participants will wear a FreeStyle Libre Pro CGM sensor (Abbott) and will receive mobile phone–based EMA prompts 6 times per day (randomly within six 2-hour windows between 8 AM and 8 PM) to assess positive and negative affect. Participants will also wear a Fitbit Inspire 2 (Fitbit) to continuously monitor physical activity and sleep, which will be included as covariates in the analysis. Multilevel linear regression models will be used to evaluate the acute relationship between glucose level and affect. Results Recruitment started in October 2022 and is expected to be completed in March 2023. We will aim to recruit 100 participants. As of December 12, 2022, a total of 39 participants have been enrolled. Conclusions The results of this study will further elucidate the role of affect in glucose variability. By identifying affective states that may lead to glucose excursions, our findings could inform just-in-time behavioral interventions by indicating opportunities for intervention delivery. International Registered Report Identifier (IRRID) DERR1-10.2196/45104

show abstract

Interstitial glucose and subsequent affective and physical feeling states: A pilot study combining continuous glucose monitoring and ecological momentary assessment in adolescents

Cited by 12 publications

References 60 publications

Putting the spotlight on individual-specific psychosomatic processes: An introduction to the special issue on intensive longitudinal research methods in psychosomatic research

Putting the spotlight on individual-specific psychosomatic processes: An introduction to the special issue on intensive longitudinal research methods in psychosomatic research

Time-Varying Associations Between Device-Based and Ecological Momentary Assessment–Reported Sedentary Behaviors and the Concurrent Affective States Among Adolescents: Proof-of-Concept Study

Real-time Assessment of the Bidirectional Relationship Between Affective States and Glucose: Protocol for a 14-Day Observational Study

Contact Info

Product

Resources

About