Intersegmental connections and interactions of myelinated somatic and visceral afferents with sympathetic preganglionic neurons in the unanesthetized spinal cat

Laskey, W.; Schondorf, R.; Polosa, Canio

doi:10.1016/0165-1838(79)90006-7

Cited by 17 publications

(1 citation statement)

References 14 publications

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“…Anatomic and functional results of an experiment have shown that the sympathetic neurons projecting to forelimb nerves are located in the cervical and stellate ganglia of sympathetic trunk as well . In 1973, Laskey et al found that the majority of the sympathetic preganglionic neurons with axons projecting to the cervical sympathetic trunk receive input from somatic afferents via intraspinal pathways, which indicated that MNS has the potential to reduce the sympathetic outflow through inhibiting the discharges of the sympathetic preganglionic neurons. However, there are no evidence to prove this mechanism directly and no experiment to show whether the sympathetic neurons projecting to the forelimbs are also innervating the heart, but we think that it is worthy to study deeply in the future.…”

Section: Discussionmentioning

confidence: 99%

Chronic median nerve modulation reduces ventricular arrhythmia and improves ventricular function in a postmyocardial infarction rabbit model

Zhai

Zhao

Tang

et al. 2018

Cardiovascular Therapeutics

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Section: Discussionmentioning

confidence: 99%

Chronic median nerve modulation reduces ventricular arrhythmia and improves ventricular function in a postmyocardial infarction rabbit model

Zhai

Zhao

Tang

et al. 2018

Cardiovascular Therapeutics

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Sympathetic Preganglionic Neurons: Properties and Inputs

Deuchars

Lall

2015

Comprehensive Physiology

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The sympathetic nervous system comprises one half of the autonomic nervous system and participates in maintaining homeostasis and enabling organisms to respond in an appropriate manner to perturbations in their environment, either internal or external. The sympathetic preganglionic neurons (SPNs) lie within the spinal cord and their axons traverse the ventral horn to exit in ventral roots where they form synapses onto postganglionic neurons. Thus, these neurons are the last point at which the central nervous system can exert an effect to enable changes in sympathetic outflow. This review considers the degree of complexity of sympathetic control occurring at the level of the spinal cord. The morphology and targets of SPNs illustrate the diversity within this group, as do their diverse intrinsic properties which reveal some functional significance of these properties. SPNs show high degrees of coupled activity, mediated through gap junctions, that enables rapid and coordinated responses; these gap junctions contribute to the rhythmic activity so critical to sympathetic outflow. The main inputs onto SPNs are considered; these comprise afferent, descending, and interneuronal influences that themselves enable functionally appropriate changes in SPN activity. The complexity of inputs is further demonstrated by the plethora of receptors that mediate the different responses in SPNs; their origins and effects are plentiful and diverse. Together these different inputs and the intrinsic and coupled activity of SPNs result in the rhythmic nature of sympathetic outflow from the spinal cord, which has a variety of frequencies that can be altered in different conditions.

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Spinal Factors in Sympathetic Regulation

Schramm

1986

Central and Peripheral Mechanisms of Cardiovascular Regulation

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Intersegmental connections and interactions of myelinated somatic and visceral afferents with sympathetic preganglionic neurons in the unanesthetized spinal cat

Cited by 17 publications

References 14 publications

Chronic median nerve modulation reduces ventricular arrhythmia and improves ventricular function in a postmyocardial infarction rabbit model

Chronic median nerve modulation reduces ventricular arrhythmia and improves ventricular function in a postmyocardial infarction rabbit model

Sympathetic Preganglionic Neurons: Properties and Inputs

Spinal Factors in Sympathetic Regulation

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