Intersection of Intimate Partner Violence and Pre-Exposure Prophylaxis: Exploring HIV Worry and PrEP Acceptability Among Women

O’Malley, Teagen; Egan, James E.; Hawk, Mary; Krier, Sarah; Burke, Jessica G.

doi:10.1177/1077801220969874

Cited by 7 publications

(6 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A growing body of literature has focused on PrEP's ability to protect women from HIV in the context of IPV and other forms of sexual violence (Bazzi et al, 2019;Braksmajer et al, 2016;Hartmann et al, 2016;O'Malley et al, 2020;Roberts et al, 2016;Willie et al, 2017Willie et al, , 2018. The pre-biomedical era of HIV prevention required condom use negotiation between partners -regardless of whether a male or female condom was used -a challenge in the face of unequal power dynamics, reproductive coercion, and potential violence.…”

Section: How Has Prep Changed Sex For Cisgender Women?mentioning

confidence: 99%

“…Thus, with PrEP's approval, experts quickly identified how PrEP could shift HIV prevention from an interpersonal negotiation to a strategy enacted autonomously and covertly, and increasing women's control over their sexual health (Braksmajer et al, 2016). However, studies of PrEP's hypothetical and actual impact on women facing violence have yielded mixed results (O'Malley et al, 2020). For example, although studies report moderate to high interest in PrEP among women with IPV histories, several unique barriers to use have been identified (O'Malley et al, 2020).…”

Section: How Has Prep Changed Sex For Cisgender Women?mentioning

confidence: 99%

“…However, studies of PrEP's hypothetical and actual impact on women facing violence have yielded mixed results (O'Malley et al, 2020). For example, although studies report moderate to high interest in PrEP among women with IPV histories, several unique barriers to use have been identified (O'Malley et al, 2020). A few studies have reported that partner resistance to daily oral PrEP acts as a barrier to use and adherence for women who have experienced IPV, with partners assuming infidelity, undisclosed seropositivity, or lack of trust as a result of women's PrEP use (Braksmajer et al, 2019;Roberts et al, 2016;Willie et al, 2017).…”

Section: How Has Prep Changed Sex For Cisgender Women?mentioning

confidence: 99%

See 2 more Smart Citations

How Has HIV Pre-Exposure Prophylaxis (PrEP) Changed Sex? A Review of Research in a New Era of Bio-behavioral HIV Prevention

Grov

Westmoreland

D’Angelo

et al. 2021

The Journal of Sex Research

View full text Add to dashboard Cite

In 2012, the U.S. FDA approved the first drug for use as HIV Pre-Exposure Prophylaxis (PrEP), which is nearly 99% effective when taken as prescribed. Although the manifest function of PrEP is to prevent HIV infection in the event of exposure, the drug has also had a significant impact on various facets of sexuality. In this review, we focus on research that emerged in the near decade since PrEP's approval, with a specific focus on the ways in which different elements of sex and sexuality have been impacted by gay, bisexual, and other men who have sex with men (GBMSM), cisgender women, and transgender individuals. We highlight evidence showing how PrEP has enhanced sexual self-esteem, improved sexual pleasure, reduced sexual anxiety, and has increased sexual agency for those taking it. For many, PrEP also serves as a gateway to improve routine health and increase sexual health-care utilization. Additionally, we review the question of whether PrEP is associated with increased sexual risk taking (i.e. risk compensation), and note that, although some data are mixed, PrEP is not intended as an intervention to reduce condomless anal sex or STIs: it aims to prevent HIV. Finally, our review highlights that, although the volume of research on PrEP among GBMSM is robust, it is underdeveloped for cisgender women and transgender populations and insufficient for inclusion in such a review for cisgender heterosexual men was. PrEP research with these populations is an important direction for future research. Finally, from 2012 to 2019, a single PrEP formulation and delivery method was FDA approved (oral emtricitabine/tenofovir disoproxil fumarate). As additional drug formulations (ie.g., emtricitabine/tenofovir alafenamide) and delivery methods (e.g., microbiocides, vaginal ring, injectable) come to market, it will be important to examine how these, too, impact the spectrum of sexuality.

show abstract

Section: How Has Prep Changed Sex For Cisgender Women?mentioning

confidence: 99%

Section: How Has Prep Changed Sex For Cisgender Women?mentioning

confidence: 99%

Section: How Has Prep Changed Sex For Cisgender Women?mentioning

confidence: 99%

See 1 more Smart Citation

How Has HIV Pre-Exposure Prophylaxis (PrEP) Changed Sex? A Review of Research in a New Era of Bio-behavioral HIV Prevention

Grov

Westmoreland

D’Angelo

et al. 2021

The Journal of Sex Research

View full text Add to dashboard Cite

show abstract

“…Factors that correlated with less PrEP interest and less comfort talking about PrEP included higher perceived stereotypes about PrEP and higher expected disapproval from friends and family. Forty-four percent of female study participants who had at least one sexual encounter with a male partner in the previous 12 months stated in a mixed methods study in Pittsburg that concerns that their partner would think they were cheating or did not trust them deterred these women from taking PrEP [30].…”

Section: Resultsmentioning

confidence: 99%

Provision of HIV preexposure prophylaxis to female patients seeking family planning services in the United States

Satish

Bravo

McAllister

et al. 2022

Aids

View full text Add to dashboard Cite

Objective:We conducted a scoping review to assess barriers to and facilitators of integrating HIV preexposure prophylaxis (PrEP) and family planning (FP) at the patient, provider, and implementation levels, and to identify gaps in knowledge.Methods:We conducted a search of five bibliographic databases from database inception to March 2022: PubMed, CINAHL, Embase, Web of Science and Scopus. Two reviewers screened abstracts and full texts to determine eligibility based on a priori inclusion and exclusion criteria. We categorized studies by their relevance to patient, provider, and implementation barriers, and extracted data based on prespecified elements.Results:Our initial search strategy yielded 1151 results, and 34 publications were included. Barriers to PrEP implementation in family planning settings included low PrEP knowledge among patients, hesitance to take PrEP due to perceived stigma, decreased willingness of providers unfamiliar with PrEP to prescribe PrEP, and limited financial and staffing resources that make prescribing and monitoring PrEP difficult. Facilitators included robust training for providers, stigma reduction efforts, leadership engagement, and increased resources specifically in settings with processes in place that ease the process of prescribing and monitoring PrEP.Conclusions:Advances in implementation strategy development, stigma reduction, and drug development will be essential to reinforcing PrEP care in family planning settings and thereby reducing the incidence of HIV in women through highly effective pharmacologic HIV prevention methods.

show abstract

“…Exposure to GBV has a causal association with incidence of HIV infection [ 20 ]. Multiple studies have documented pathways between exposure to violence and women’s vulnerability to HIV [ 9 , 16 , 21 , 22 ]. Such pathways include direct infection from forced sexual intercourse and associated genital trauma.…”

Section: Introductionmentioning

confidence: 99%

Impact of DREAMS interventions on experiences of violence among adolescent girls and young women: Findings from population-based cohort studies in Kenya and South Africa

Wambiya

Gourlay

Mulwa

et al. 2023

PLOS Glob Public Health

View full text Add to dashboard Cite

DREAMS aims to reduce HIV incidence among adolescent girls and young women (AGYW) by tackling drivers of HIV risk including gender-based violence. We evaluate the impact of DREAMS on recent experiences of violence perpetuated by men against AGYW. AGYW cohorts were randomly selected from demographic platforms in South Africa (rural KwaZulu-Natal) and Kenya (Nairobi informal settlements and rural Gem sub-county). AGYW aged 13–22 years were enrolled in 2017 (Nairobi, KwaZulu-Natal) or 2018 (Gem), with annual follow-up to 2019. We described proportions of AGYW who self-reported experiences of violence perpetrated by males in the 12 months preceding the interview, overall and by form (physical, sexual, emotional). We investigated associations with DREAMS (invitation to participate during 2017–2018) through multivariable propensity score-adjusted logistic regression and estimated the causal effect of DREAMS on experiences of violence, under counter-factual scenarios in which all versus no AGYW were DREAMS beneficiaries. Among 852, 1018 and 1712 AGYW followed-up in 2019 in Nairobi, Gem and KZN, respectively, proportions reporting any violence in 2019 were higher in Nairobi (29%) than Gem (18%) and KwaZulu-Natal (19%). By sub-type, emotional and physical violence were more frequently reported than sexual violence. We found no evidence of an impact attributable to DREAMS on overall levels of violence, in any setting. Nor was there evidence of impact on sub-types of violence, with one exception: an increase in physical violence in Nairobi if all, versus no, AGYW were DREAMS beneficiaries (16% vs 11%; +5% difference [95% CI: +0.2%, +10.0%]). Experiences of gender-based violence were common among AGYW, especially in urban settings, and DREAMS had no measurable impact on reducing violence within three years of implementation. Violence prevention programming that reaches more men and the broader community, sustained for longer periods, may yield greater gains in violence reduction than AGYW-focused programming. Additionally, more investment in implementation research is needed to bridge trial-based study findings from efficacy to population-level effectiveness.

show abstract

Intersection of Intimate Partner Violence and Pre-Exposure Prophylaxis: Exploring HIV Worry and PrEP Acceptability Among Women

Cited by 7 publications

References 40 publications

How Has HIV Pre-Exposure Prophylaxis (PrEP) Changed Sex? A Review of Research in a New Era of Bio-behavioral HIV Prevention

How Has HIV Pre-Exposure Prophylaxis (PrEP) Changed Sex? A Review of Research in a New Era of Bio-behavioral HIV Prevention

Provision of HIV preexposure prophylaxis to female patients seeking family planning services in the United States

Impact of DREAMS interventions on experiences of violence among adolescent girls and young women: Findings from population-based cohort studies in Kenya and South Africa

Contact Info

Product

Resources

About