Interrupter Technique Revisited: Building an Experimental Mechanical Ventilator to Assess Respiratory Mechanics in Large Animals
Camilla Zilianti,
Erfan Bashar,
Anna Kyriakoudi
et al.
Abstract:Large animals are increasingly used as experimental models of respiratory diseases. Precise characterization of respiratory mechanics requires dedicated equipment with specific characteristics which are difficult to find together in the same commercial device. In this work, we describe building and validation of a computer-controlled ventilator able to perform rapid airways occlusions during constant flow inflations followed by a prolonged inspiratory hold. A constant airflow is provided by a high pressure sou… Show more
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